(data stored in ACNUC15324 zone)

HOGENOM: RAT13_PE148

ID   RAT13_PE148                          STANDARD;      PRT;   183 AA.
AC   RAT13_PE148; Q9JI24;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Interleukin-24; Short=IL-24;AltName: Full=Cytokine-like
DE   protein Mob-5;Flags: Precursor; (RAT13.PE148).
GN   Name=Il24; Synonyms=Mob5;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT13.PE148.
CC       Rattus norvegicus chromosome 13 RGSC3.4  sequence 1..111154910
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:IL24_RAT
CC   -!- FUNCTION: Has antiproliferative properties on melanoma cells and
CC       may contribute to terminal cell differentiation (By similarity).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the IL-10 family.
CC   -!- GENE_FAMILY: HOG000113033 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000004470;ENSRNOT00000006106;ENSRNOP00000006106.
DR   EMBL; AF004774; - ;
DR   EMBL; AF269251; - ;
DR   UniProtKB/Swiss-Prot; Q9JI24; -.
DR   EMBL; AF269251; AAF75553.1; -; mRNA.
DR   IPI; IPI00199809; -.
DR   RefSeq; NP_579845.1; NM_133311.1.
DR   UniGene; Rn.48710; -.
DR   ProteinModelPortal; Q9JI24; -.
DR   STRING; Q9JI24; -.
DR   PRIDE; Q9JI24; -.
DR   Ensembl; ENSRNOT00000006106; ENSRNOP00000006106; ENSRNOG00000004470.
DR   GeneID; 170819; -.
DR   KEGG; rno:170819; -.
DR   NMPDR; fig|10116.3.peg.9035; -.
DR   UCSC; NM_133311; rat.
DR   CTD; 11009; -.
DR   RGD; 621484; Il24.
DR   eggNOG; roNOG16189; -.
DR   InParanoid; Q9JI24; -.
DR   OMA; QFGPCRV; -.
DR   OrthoDB; EOG4ZPDW8; -.
DR   PhylomeDB; Q9JI24; -.
DR   NextBio; 621231; -.
DR   ArrayExpress; Q9JI24; -.
DR   Genevestigator; Q9JI24; -.
DR   GermOnline; ENSRNOG00000004470; Rattus norvegicus.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptosis; IEA:UniProtKB-KW.
DR   GO; GO:0048144; P:fibroblast proliferation; TAS:RGD.
DR   GO; GO:0042060; P:wound healing; TAS:RGD.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR012351; 4_helix_cytokine_core.
DR   InterPro; IPR020443; Interleukin-10/19/20/24.
DR   InterPro; IPR020423; Interleukin-10_CS.
DR   InterPro; IPR020444; Interleukin-24.
DR   Gene3D; G3DSA:1.20.1250.10; 4_helix_cytokine_core; 1.
DR   PANTHER; PTHR11585; Interleukin_10; 1.
DR   PRINTS; PR01937; INTRLEUKIN24.
DR   SUPFAM; SSF47266; 4_helix_cytokine; 1.
DR   PROSITE; PS00520; INTERLEUKIN_10; 1.
DR   HOGENOMDNA; RAT13.PE148; -.
KW   ENSRNOG00000004470820036002503210000011;
KW   Il24; IL24_RAT; Q9WVP8_RAT; AF004774; AF269251;
KW   Apoptosis; Complete proteome; Cytokine; Glycoprotein;
KW   Reference proteome; Secreted; Signal.
SQ   SEQUENCE   183 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQTSLRQQIL PGLSLILLVL NQVPELQGQE FRFGPCQVTG VVLPELWEAF WTVKNTVKTQ
     DELTSVRLLK PQVLQNVSDA ESCYLAHSLL KFYLNTVFKN YHSKIVKFKV LKSFSTLANN
     FLVIMSKLQP SKDNAMLPIS DSARRRFLLY HRTFKQLDIE VALAKAFGEV DILLAWMQNF
     YQL
//

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