(data stored in ACNUC17492 zone)

HOGENOM: RAT13_PE358

ID   RAT13_PE358                          STANDARD;      PRT;   162 AA.
AC   RAT13_PE358; P97844; Q4KM99;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 1; Short=RGS1;
DE   (RAT13.PE358).
GN   Name=Rgs1;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT13.PE358.
CC       Rattus norvegicus chromosome 13 RGSC3.4  sequence 1..111154910
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS1_RAT
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form (By similarity).
CC   -!- TISSUE SPECIFICITY: Expressed in multiple tissues.
CC   -!- PTM: Could be phosphorylated. Might be functionally regulated by
CC       protein kinase(s) (By similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000003895;ENSRNOT00000005251;ENSRNOP00000005251.
DR   EMBL; BC098681; - ;
DR   EMBL; U77698; - ;
DR   UniProtKB/Swiss-Prot; P97844; Q4KM99; -.
DR   EMBL; BC098681; AAH98681.1; -; mRNA.
DR   EMBL; U77698; AAB48300.1; -; mRNA.
DR   IPI; IPI00358927; -.
DR   RefSeq; NP_062209.1; NM_019336.1.
DR   UniGene; Rn.14787; -.
DR   ProteinModelPortal; P97844; -.
DR   SMR; P97844; 24-157.
DR   STRING; P97844; -.
DR   PRIDE; P97844; -.
DR   Ensembl; ENSRNOT00000005251; ENSRNOP00000005251; ENSRNOG00000003895.
DR   GeneID; 54289; -.
DR   KEGG; rno:54289; -.
DR   UCSC; NM_019336; rat.
DR   CTD; 5996; -.
DR   RGD; 3561; Rgs1.
DR   eggNOG; roNOG13361; -.
DR   GeneTree; ENSGT00600000084096; -.
DR   InParanoid; P97844; -.
DR   OrthoDB; EOG42822Z; -.
DR   NextBio; 610888; -.
DR   ArrayExpress; P97844; -.
DR   Genevestigator; P97844; -.
DR   GermOnline; ENSRNOG00000003895; Rattus norvegicus.
DR   GO; GO:0005737; C:cytoplasm; IBA:RefGenome.
DR   GO; GO:0005886; C:plasma membrane; IBA:RefGenome.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 2.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; RAT13.PE358; -.
KW   ENSRNOG00000003895820036002503210000011;
KW   Rgs1; RGS1_RAT; BC098681; U77698;
KW   Complete proteome; Reference proteome; Signal transduction inhibitor.
SQ   SEQUENCE   162 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDMKAYLRSM IPHLESGMKS SKSKDILSAE EVMQWSQSLE KLLANQMGQN VFGKFLKSEF
     SEENIEFWLA CEDYKKTETD LLHNKAEHIY KAFVHSDAVK QINIDFHTRE STAKKIKTPT
     PTCFDEAQKV IYALMEKDSY PRFLKSNIYL NLLNDLQANT LK
//

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