(data stored in ACNUC17492 zone)

HOGENOM: RAT13_PE650

ID   RAT13_PE650                          STANDARD;      PRT;   180 AA.
AC   RAT13_PE650; P49800; Q9JKD7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 5; Short=RGS5;
DE   (RAT13.PE650).
GN   Name=Rgs5;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT13.PE650.
CC       Rattus norvegicus chromosome 13 RGSC3.4  sequence 1..111154910
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS5_RAT
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha,
CC       but not to G(s)-alpha (By similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000002730;ENSRNOT00000003705;ENSRNOP00000003705.
DR   EMBL; AF241259; - ;
DR   EMBL; EF568934; - ;
DR   EMBL; U32435; - ;
DR   UniProtKB/Swiss-Prot; P49800; Q9JKD7; -.
DR   EMBL; AF241259; AAF73424.1; -; mRNA.
DR   EMBL; U32435; AAC52372.1; -; mRNA.
DR   IPI; IPI00198041; -.
DR   RefSeq; NP_062214.1; NM_019341.1.
DR   UniGene; Rn.1150; -.
DR   ProteinModelPortal; P49800; -.
DR   SMR; P49800; 44-181.
DR   STRING; P49800; -.
DR   GeneID; 54294; -.
DR   KEGG; rno:54294; -.
DR   CTD; 8490; -.
DR   RGD; 3568; Rgs5.
DR   eggNOG; maNOG17871; -.
DR   GeneTree; ENSGT00600000084096; -.
DR   OrthoDB; EOG41RPW5; -.
DR   NextBio; 610912; -.
DR   ArrayExpress; P49800; -.
DR   Genevestigator; P49800; -.
DR   GermOnline; ENSRNOG00000002730; Rattus norvegicus.
DR   GO; GO:0005737; C:cytoplasm; IBA:RefGenome.
DR   GO; GO:0005886; C:plasma membrane; IBA:RefGenome.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; RAT13.PE650; -.
KW   ENSRNOG00000002730820036002503210000011;
KW   Rgs5; RGS5_RAT; A5YN34_RAT; AF241259; EF568934; U32435;
KW   Complete proteome; Reference proteome; Signal transduction inhibitor.
SQ   SEQUENCE   180 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCKGLAALPH SCLERAKEIK IKLGILLQKP DSAVDLVIPY NEKPEKPAKA HKPSLEEVLQ
     WRQSLDKLLQ SNYGFASFKS LLKSEFSEEN LEFWVACENY KIKSPIKMAE KAKQIYEEII
     QTEAXKEVNI DHFTKDITMK NLVEPSPHSF DLAQKRIYAL MEKDSLPRFV RSEFYKELIN
//

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