(data stored in ACNUC7421 zone)

HOGENOM: RAT1_PE1236

ID   RAT1_PE1236                          STANDARD;      PRT;   327 AA.
AC   RAT1_PE1236; Q62651;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial;
DE   EC=5.3.3 -;Flags: Precursor; (RAT1.PE1236).
GN   Name=Ech1;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT1.PE1236.
CC       Rattus norvegicus chromosome 1 RGSC3.4  sequence 1..267910886
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:ECH1_RAT
CC   -!- FUNCTION: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-
CC       trans-dienoyl-CoA.
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC   -!- SUBUNIT: Homohexamer.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion. Peroxisome.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC   -!- GENE_FAMILY: HOG000027939 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000020308;ENSRNOT00000027537;ENSRNOP00000027537.
DR   EMBL; BC062226; - ;
DR   EMBL; U08976; - ;
DR   UniProtKB/Swiss-Prot; Q62651; -.
DR   EMBL; U08976; AAA82008.1; -; mRNA.
DR   EMBL; BC062226; AAH62226.1; -; mRNA.
DR   IPI; IPI00326561; -.
DR   PIR; A57626; A57626.
DR   RefSeq; NP_072116.1; NM_022594.1.
DR   UniGene; Rn.6148; -.
DR   PDB; 1DCI; X-ray; 1.50 A; A/B/C=54-327.
DR   PDBsum; 1DCI; -.
DR   ProteinModelPortal; Q62651; -.
DR   SMR; Q62651; 54-327.
DR   MINT; MINT-4597589; -.
DR   STRING; Q62651; -.
DR   Rat-heart-2DPAGE; Q62651; -.
DR   PRIDE; Q62651; -.
DR   Ensembl; ENSRNOT00000027537; ENSRNOP00000027537; ENSRNOG00000020308.
DR   GeneID; 64526; -.
DR   KEGG; rno:64526; -.
DR   UCSC; BC060565; rat.
DR   CTD; 1891; -.
DR   RGD; 69353; Ech1.
DR   eggNOG; roNOG16501; -.
DR   GeneTree; ENSGT00580000081296; -.
DR   InParanoid; Q62651; -.
DR   OMA; HTNQEGL; -.
DR   OrthoDB; EOG4VQ9PW; -.
DR   PhylomeDB; Q62651; -.
DR   NextBio; 613350; -.
DR   ArrayExpress; Q62651; -.
DR   Genevestigator; Q62651; -.
DR   GermOnline; ENSRNOG00000020308; Rattus norvegicus.
DR   GO; GO:0005739; C:mitochondrion; IDA:UniProtKB.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001753; Crotonase_core.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   Pfam; PF00378; ECH; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
DR   HOGENOMDNA; RAT1.PE1236; -.
KW   ENSRNOG00000020308820036002503210000011;
KW   Ech1; ECH1_RAT; BC062226; U08976;
KW   3D-structure; Acetylation; Complete proteome;
KW   Direct protein sequencing; Fatty acid metabolism; Isomerase;
KW   Lipid metabolism; Metal-binding; Mitochondrion; Peroxisome;
KW   Phosphoprotein; Reference proteome; Transit peptide; Zinc;
KW   Zinc-finger.
SQ   SEQUENCE   327 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATAMTVSSK LLGLLMQQLR GTRQLYFNVS LRSLSSSAQE ASKRIPEEVS DHNYESIQVT
     SAQKHVLHVQ LNRPEKRNAM NRAFWRELVE CFQKISKDSD CRAVVVSGAG KMFTSGIDLM
     DMASDILQPP GDDVARIAWY LRDLISRYQK TFTVIEKCPK PVIAAIHGGC IGGGVDLISA
     CDIRYCTQDA FFQVKEVDVG LAADVGTLQR LPKVIGNRSL VNELTFTARK MMADEALDSG
     LVSRVFPDKD VMLNAAFALA ADISSKSPVA VQGSKINLIY SRDHSVDESL DYMATWNMSM
     LQTQDIIKSV QAAMEKKDSK SITFSKL
//

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