(data stored in ACNUC21562 zone)

HOGENOM: RAT1_PE1675

ID   RAT1_PE1675                          STANDARD;      PRT;   331 AA.
AC   RAT1_PE1675; Q7TN49; Q5FVU1; Q91YB7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Mas-related G-protein coupled receptor member A;
DE   (RAT1.PE1675).
GN   Name=Mrgpra; Synonyms=Mrga;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT1.PE1675.
CC       Rattus norvegicus chromosome 1 RGSC3.4  sequence 1..267910886
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:MRGRA_RAT
CC   -!- FUNCTION: Orphan receptor activated by a subset of RFamide-family
CC       neuropeptides such as FLRF-amide and FMRF-amide. Mediates its
CC       action by association with G proteins that activate a
CC       phosphatidylinositol-calcium second messenger system. Its effect
CC       is mediated by G(q) and G(11) proteins. May regulate the function
CC       of nociceptive neurons by modulation of pain perception (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Expressed in a subset of IB4-positive small
CC       diameter nociceptive dorsal root neurons.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Mas subfamily.
CC   -!- CAUTION: Was originally (PubMed:12084918) thought to be an adenine
CC       receptor but PubMed:12397184 found no activation by adenine of the
CC       mouse ortholog.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH89774.1; Type=Erroneous initiation;
CC       Sequence=CAC84592.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000015412 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000014227;ENSRNOT00000019051;ENSRNOP00000019051.
DR   EMBL; AF518238; - ;
DR   EMBL; AJ311952; - ;
DR   EMBL; BC089774; - ;
DR   UniProtKB/Swiss-Prot; Q7TN49; Q5FVU1; Q91YB7; -.
DR   EMBL; AJ311952; CAC84592.1; ALT_INIT; mRNA.
DR   EMBL; AF518238; AAQ08310.1; -; Genomic_DNA.
DR   EMBL; BC089774; AAH89774.1; ALT_INIT; mRNA.
DR   IPI; IPI00785558; -.
DR   RefSeq; NP_665730.2; NM_145787.2.
DR   UniGene; Rn.81069; -.
DR   ProteinModelPortal; Q7TN49; -.
DR   PRIDE; Q7TN49; -.
DR   GeneID; 252960; -.
DR   KEGG; rno:252960; -.
DR   NMPDR; fig|10116.3.peg.1933; -.
DR   UCSC; BC089774; rat.
DR   CTD; 117195; -.
DR   RGD; 738050; Mrgpra.
DR   eggNOG; maNOG18315; -.
DR   GeneTree; ENSGT00550000074531; -.
DR   InParanoid; Q7TN49; -.
DR   OrthoDB; EOG451DRQ; -.
DR   NextBio; 624138; -.
DR   ArrayExpress; Q7TN49; -.
DR   Genevestigator; Q7TN49; -.
DR   GermOnline; ENSRNOG00000014227; Rattus norvegicus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:RGD.
DR   InterPro; IPR000276; 7TM_GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_supfam.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   HOGENOMDNA; RAT1.PE1675; -.
KW   ENSRNOG00000014227820036002503210000011;
KW   Mrga10; MRGRA_RAT; AF518238; AJ311952; BC089774;
KW   Cell membrane; Complete proteome; G-protein coupled receptor;
KW   Membrane; Receptor; Reference proteome; Transducer; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   331 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGESFTGTGF INLNTSASTI AVTTTNPMDK TIPGSFNSRT LIPNLLIIIS GLVGLIGNAM
     VFWLLGFRLA RNAFSVYILN LALADFLFLL CHIIDSTLLL LKFSYPNIIF LPCFNTVMMV
     PYIAGLSMLS AISTERCLSV VCPIWYRCRR PKHTSTVMCS AIWVLSLLIC ILNRYFCGFL
     DTKYEKDNRC LASNFFTAAC LIFLFVVLCL SSLALLVRLF CGAGRMKLTR LYATIMLTVL
     VFLLCGLPFG IHWFLLIWIK IDYGKFAYGL YLAALVLTAV NSCANPIIYF FVGSFRHQKH
     QTLKMVLQRA LQDTPETAEN TVEMSSSKVE P
//

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