(data stored in ACNUC21562 zone)

HOGENOM: RAT1_PE1677

ID   RAT1_PE1677                          STANDARD;      PRT;   337 AA.
AC   RAT1_PE1677; Q8R4G1; Q7TN42;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Mas-related G-protein coupled receptor member X1;AltName:
DE   Full=Sensory neuron-specific G-protein coupled receptor 1; (RAT1.PE1677).
GN   Name=Mrgprx1; Synonyms=Mrgc, Mrgprc, Mrgprc11, Snsr, Snsr1;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT1.PE1677.
CC       Rattus norvegicus chromosome 1 RGSC3.4  sequence 1..267910886
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:MRGX1_RAT
CC   -!- FUNCTION: Orphan receptor activated by neuropeptides terminating
CC       in Arg-Phe or Arg-Phe-amide. Mediates its action by association
CC       with G proteins that activate a phosphatidylinositol-calcium
CC       second messenger system. Its effect is mediated by G(q) and G(11)
CC       proteins. May regulate the function of nociceptive neurons by
CC       modulation of pain perception (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Uniquely localized in a subset of small dorsal
CC       root and trigeminal sensory neurons. Associated preferentially
CC       with IB4 class of small-diameter somatosensory afferents (also
CC       known as nociceptors).
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Mas subfamily.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL86877.2; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000015412 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000014242;ENSRNOT00000019061;ENSRNOP00000019061.
DR   EMBL; AF474986; - ;
DR   EMBL; AF518245; - ;
DR   UniProtKB/Swiss-Prot; Q8R4G1; Q7TN42; -.
DR   EMBL; AF474986; AAL86877.2; ALT_INIT; Genomic_DNA.
DR   EMBL; AF518245; AAQ08317.1; -; Genomic_DNA.
DR   IPI; IPI00200680; -.
DR   RefSeq; NP_001002286.1; NM_001002286.1.
DR   RefSeq; NP_750845.2; NM_172158.2.
DR   UniGene; Rn.138128; -.
DR   ProteinModelPortal; Q8R4G1; -.
DR   STRING; Q8R4G1; -.
DR   GeneID; 282547; -.
DR   GeneID; 404646; -.
DR   KEGG; rno:282547; -.
DR   KEGG; rno:404646; -.
DR   CTD; 259249; -.
DR   CTD; 404646; -.
DR   RGD; 632284; Mrgprx1.
DR   eggNOG; roNOG15951; -.
DR   GeneTree; ENSGT00550000074531; -.
DR   InParanoid; Q8R4G1; -.
DR   OrthoDB; EOG4MW86R; -.
DR   Genevestigator; Q8R4G1; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000276; 7TM_GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_supfam.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   HOGENOMDNA; RAT1.PE1677; -.
KW   ENSRNOG00000014242820036002503210000011;
KW   Mrgprc; Mrgprx1; MRGX1_RAT; AF474986; AF518245;
KW   Cell membrane; Complete proteome; G-protein coupled receptor;
KW   Glycoprotein; Membrane; Receptor; Reference proteome; Transducer;
KW   Transmembrane; Transmembrane helix.
SQ   SEQUENCE   337 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVCVLRDTTG RFVSMDPTIS SLSTESTTLN KTGHPSCRPI LTLSFLVPII TLLGLAGNTI
     VLWLLGFRMR RKAISVYVLN LSLADSFFLC CHFIDSLMRI MNFYGIYAHK LSKEILGNAA
     IIPYISGLSI LSAISTERCL SVLWPIWYHC HRPRNMSAII CVLIWVLSFL MGILDWFFSG
     FLGETHHHLW KNVDFIVTAF LIFLFMLLFG SSLALLVRIL CGSRRKPLSR LYVTISLTVM
     VYLICGLPLG LYLFLLYWFG IHLHYPFCHI YQVTVLLSCV NSSANPIIYF LVGSFRHRKK
     HRSLKMVLKR ALEETPEEDE YTDSHVQKPT EISERRC
//

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