(data stored in ACNUC26070 zone)

HOGENOM: RAT1_PE2116

ID   RAT1_PE2116                          STANDARD;      PRT;   107 AA.
AC   RAT1_PE2116; Q9JJV7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Potassium voltage-gated channel subfamily E member
DE   3;AltName: Full=MinK-related peptide 2;AltName: Full=Minimum potassium
DE   ion channel-related peptide 2;AltName: Full=Potassium channel subunit
DE   beta MiRP2; (RAT1.PE2116).
GN   Name=Kcne3;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT1.PE2116.
CC       Rattus norvegicus chromosome 1 RGSC3.4  sequence 1..267910886
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCNE3_RAT
CC   -!- FUNCTION: Ancillary protein that assembles as a beta subunit with
CC       a voltage-gated potassium channel complex of pore-forming alpha
CC       subunits. Modulates the gating kinetics and enhances stability of
CC       the channel complex. Associated with KCNC4/Kv3.4 is proposed to
CC       form the subthreshold voltage-gated potassium channel in skeletal
CC       muscle and to establish the resting membrane potential (RMP) in
CC       muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal
CC       cAMP-stimulated potassium channel involved in chloride secretion
CC       (By similarity).
CC   -!- SUBUNIT: Associates with KCNC4/Kv3.4. May associate with
CC       KCNQ1/KVLQT1 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the potassium channel KCNE family.
CC   -!- GENE_FAMILY: HOG000113209 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000017054;ENSRNOT00000048437;ENSRNOP00000044706.
DR   EMBL; AJ271742; - ;
DR   EMBL; BC086406; - ;
DR   UniProtKB/Swiss-Prot; Q9JJV7; -.
DR   EMBL; AJ271742; CAB72139.1; -; mRNA.
DR   EMBL; BC086406; AAH86406.1; -; mRNA.
DR   IPI; IPI00202076; -.
DR   RefSeq; NP_071571.1; NM_022235.2.
DR   UniGene; Rn.44843; -.
DR   STRING; Q9JJV7; -.
DR   PRIDE; Q9JJV7; -.
DR   Ensembl; ENSRNOT00000048437; ENSRNOP00000044706; ENSRNOG00000017054.
DR   GeneID; 63883; -.
DR   KEGG; rno:63883; -.
DR   UCSC; NM_022235; rat.
DR   CTD; 10008; -.
DR   RGD; 621384; Kcne3.
DR   eggNOG; roNOG16470; -.
DR   GeneTree; ENSGT00390000008537; -.
DR   InParanoid; Q9JJV7; -.
DR   OMA; YKSLHAV; -.
DR   OrthoDB; EOG4B5P6P; -.
DR   PhylomeDB; Q9JJV7; -.
DR   NextBio; 612514; -.
DR   ArrayExpress; Q9JJV7; -.
DR   Genevestigator; Q9JJV7; -.
DR   GermOnline; ENSRNOG00000017054; Rattus norvegicus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:RGD.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0043266; P:regulation of potassium ion transport; IMP:RGD.
DR   InterPro; IPR000369; K_chnl_volt-dep_bsu_KCNE.
DR   InterPro; IPR005426; K_chnl_volt-dep_bsu_KCNE3.
DR   Pfam; PF02060; ISK_Channel; 1.
DR   PRINTS; PR01606; KCNE3CHANNEL.
DR   PRINTS; PR00168; KCNECHANNEL.
DR   HOGENOMDNA; RAT1.PE2116; -.
KW   ENSRNOG00000017054820036002503210000011;
KW   Kcne3; KCNE3_RAT; AJ271742; BC086406;
KW   Complete proteome; Glycoprotein; Ion transport; Ionic channel;
KW   Membrane; Potassium; Potassium channel; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport;
KW   Voltage-gated channel.
SQ   SEQUENCE   107 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     METSNGTETW YKSLHAVLKA LNTTLHSHLL CRPGPGPGSG TGPDNQTEDH RASLPGRNDN
     SYMYILFVMF LFAVTVGSLI LGYTRSRKVD KRSDPYHVYI KNRVSMI
//

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