(data stored in ACNUC21562 zone)

HOGENOM: RAT1_PE3174

ID   RAT1_PE3174                          STANDARD;      PRT;   319 AA.
AC   RAT1_PE3174; Q7TN41; Q6L788;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Mas-related G-protein coupled receptor member D;AltName:
DE   Full=Beta-alanine receptor;AltName: Full=G-protein coupled receptor TGR7;
DE   (RAT1.PE3174).
GN   Name=Mrgprd; Synonyms=Mrgd;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT1.PE3174.
CC       Rattus norvegicus chromosome 1 RGSC3.4  sequence 1..267910886
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:MRGRD_RAT
CC   -!- FUNCTION: May regulate nociceptor function and/or development,
CC       including the sensation or modulation of pain. Functions as a
CC       specific membrane receptor for beta-alanine. The receptor couples
CC       with G-protein G(q) and G(i) (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Co-expressed in the small diameter neurons
CC       with P2X3 and VR1 in dorsal root ganglia.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Mas subfamily.
CC   -!- GENE_FAMILY: HOG000015412 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000013448;ENSRNOT00000017958;ENSRNOP00000017958.
DR   EMBL; AB154411; - ;
DR   EMBL; AF518246; - ;
DR   UniProtKB/Swiss-Prot; Q7TN41; Q6L788; -.
DR   EMBL; AF518246; AAQ08318.1; -; Genomic_DNA.
DR   EMBL; AB154411; BAD20639.1; -; mRNA.
DR   IPI; IPI00197601; -.
DR   RefSeq; NP_001001506.1; NM_001001506.1.
DR   UniGene; Rn.162482; -.
DR   ProteinModelPortal; Q7TN41; -.
DR   STRING; Q7TN41; -.
DR   PRIDE; Q7TN41; -.
DR   Ensembl; ENSRNOT00000017958; ENSRNOP00000017958; ENSRNOG00000013448.
DR   GeneID; 293648; -.
DR   KEGG; rno:293648; -.
DR   NMPDR; fig|10116.3.peg.3389; -.
DR   CTD; 116512; -.
DR   RGD; 738040; Mrgprd.
DR   eggNOG; roNOG08675; -.
DR   GeneTree; ENSGT00550000074531; -.
DR   InParanoid; Q7TN41; -.
DR   OMA; FLAMATC; -.
DR   OrthoDB; EOG4MW86R; -.
DR   PhylomeDB; Q7TN41; -.
DR   NextBio; 636624; -.
DR   Genevestigator; Q7TN41; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:RGD.
DR   InterPro; IPR000276; 7TM_GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_supfam.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   HOGENOMDNA; RAT1.PE3174; -.
KW   ENSRNOG00000013448820036002503210000011;
KW   Mrgprd; MRGRD_RAT; AB154411; AF518246;
KW   Cell membrane; Complete proteome; G-protein coupled receptor;
KW   Membrane; Receptor; Reference proteome; Transducer; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   319 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNYTPYSSPA PGLTISPTMD PVTWVYFSVT FLAMATCVCG IVGNSMVIWL LSFHRVQRSP
     FCTYVLNLAV ADLLFLLCMA SLLSLETGPL LTASTSARVY EGMKRIKYFA YTAGLSLLTA
     ISTQRCLSVL FPIWYKCHRP QHLSGVVCGV LWALALLMNF LASFFCVQFW HPDKYQCFKV
     DMVFNSLILG IFMPVMVLTS AIIFIRMRKN SLLQRRQPRR LYVVILTSVL VFLTCSLPLG
     INWFLLYWVE LPQAVRLLYV CSSRFSSSLS SSANPVIYFL VGSQKSHRLQ ESLGAVLGRA
     LQDEPEGRET PSTCTNDGV
//

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