(data stored in ACNUC31108 zone)

HOGENOM: RAT2_PE1545

ID   RAT2_PE1545                          STANDARD;      PRT;   221 AA.
AC   RAT2_PE1545; Q9JJW1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Tetraspanin-2; Short=Tspan-2; (RAT2.PE1545).
GN   Name=Tspan2;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT2.PE1545.
CC       Rattus norvegicus chromosome 2 RGSC3.4  sequence 1..258207540
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:TSN2_RAT
CC   -!- FUNCTION: May play a role in signalling in oligodendrocytes in the
CC       early stages of their terminal differentiation into myelin-forming
CC       glia and may also function in stabilizing the mature sheath.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
CC       (Probable).
CC   -!- TISSUE SPECIFICITY: Expression is restricted to the nervous
CC       system.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC   -!- GENE_FAMILY: HOG000230651 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000023338;ENSRNOT00000035605;ENSRNOP00000033076.
DR   EMBL; AJ271442; - ;
DR   EMBL; BC085733; - ;
DR   UniProtKB/Swiss-Prot; Q9JJW1; -.
DR   EMBL; AJ271442; CAB69827.1; -; mRNA.
DR   EMBL; BC085733; AAH85733.1; -; mRNA.
DR   IPI; IPI00202110; -.
DR   RefSeq; NP_072111.1; NM_022589.1.
DR   UniGene; Rn.5872; -.
DR   ProteinModelPortal; Q9JJW1; -.
DR   STRING; Q9JJW1; -.
DR   Ensembl; ENSRNOT00000035605; ENSRNOP00000033076; ENSRNOG00000023338.
DR   GeneID; 64521; -.
DR   KEGG; rno:64521; -.
DR   UCSC; NM_022589; rat.
DR   CTD; 10100; -.
DR   RGD; 620982; Tspan2.
DR   eggNOG; roNOG04749; -.
DR   GeneTree; ENSGT00590000082836; -.
DR   InParanoid; Q9JJW1; -.
DR   OMA; PEYFYMG; -.
DR   OrthoDB; EOG4DZ1W7; -.
DR   PhylomeDB; Q9JJW1; -.
DR   NextBio; 613330; -.
DR   ArrayExpress; Q9JJW1; -.
DR   Genevestigator; Q9JJW1; -.
DR   GermOnline; ENSRNOG00000023338; Rattus norvegicus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043209; C:myelin sheath; IDA:RGD.
DR   GO; GO:0007420; P:brain development; IEP:RGD.
DR   InterPro; IPR023396; CD81_extracellular.
DR   InterPro; IPR018499; Tetraspanin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   InterPro; IPR000301; Tetraspanin_subgr.
DR   Gene3D; G3DSA:1.10.1450.10; G3DSA:1.10.1450.10; 1.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
DR   HOGENOMDNA; RAT2.PE1545; -.
KW   ENSRNOG00000023338820036002503210000011;
KW   Tspan2; TSN2_RAT; AJ271442; BC085733;
KW   Complete proteome; Direct protein sequencing; Glycoprotein; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   221 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGRFRGGLRC IKYLLLGFNL LFWLAGSAVI AFGLWFRFGG TIKDLSSEEK SPEYFYVGLY
     VLVGAGALMM AVGFFGCCGA MRESQCVLGS FFTCLLVIFA AEVTTGVFAF IGKDVAIRHV
     QSMYEEAYSD YVRDRGRGNG TLITFHSAFQ CCGKESSEQV QPTCPKELPG HKNCIDKIET
     IISVKLQLIG IVGIGIAGLT IFGMIFSMVL CCAIRNSRDV I
//

If you have problems or comments...

PBIL Back to PBIL home page