(data stored in ACNUC1829 zone)

HOGENOM: RAT2_PE1627

ID   RAT2_PE1627                          STANDARD;      PRT;   219 AA.
AC   RAT2_PE1627; P24485;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Leukocyte surface antigen CD53;AltName: Full=Cell surface
DE   glycoprotein CD53;AltName: Full=Leukocyte antigen MRC OX-44;AltName:
DE   CD_antigen=CD53; (RAT2.PE1627).
GN   Name=Cd53; Synonyms=Ox-44;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT2.PE1627.
CC       Rattus norvegicus chromosome 2 RGSC3.4  sequence 1..258207540
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:CD53_RAT
CC   -!- FUNCTION: May be involved in growth regulation in hematopoietic
CC       cells.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Spleen and thymus, B-cells, monocytes,
CC       macrophages, neutrophils, single (CD4 or CD8) positive thymocytes,
CC       peripheral T-cells.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC   -!- GENE_FAMILY: HOG000230651 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000017874;ENSRNOT00000024344;ENSRNOP00000024344.
DR   EMBL; BC078900; - ;
DR   EMBL; M57276; - ;
DR   UniProtKB/Swiss-Prot; P24485; -.
DR   EMBL; M57276; AAA41775.1; -; mRNA.
DR   EMBL; BC078900; AAH78900.1; -; mRNA.
DR   IPI; IPI00231743; -.
DR   PIR; A39574; A39574.
DR   RefSeq; NP_036655.1; NM_012523.1.
DR   UniGene; Rn.31988; -.
DR   STRING; P24485; -.
DR   Ensembl; ENSRNOT00000024344; ENSRNOP00000024344; ENSRNOG00000017874.
DR   GeneID; 24251; -.
DR   KEGG; rno:24251; -.
DR   NMPDR; fig|10116.3.peg.16810; -.
DR   UCSC; NM_012523; rat.
DR   CTD; 963; -.
DR   RGD; 2310; Cd53.
DR   eggNOG; roNOG10197; -.
DR   GeneTree; ENSGT00590000082914; -.
DR   InParanoid; P24485; -.
DR   OMA; VIQVLGM; -.
DR   OrthoDB; EOG4ZS94F; -.
DR   PhylomeDB; P24485; -.
DR   NextBio; 602765; -.
DR   ArrayExpress; P24485; -.
DR   Genevestigator; P24485; -.
DR   GermOnline; ENSRNOG00000017874; Rattus norvegicus.
DR   GO; GO:0009986; C:cell surface; IDA:RGD.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; NAS:RGD.
DR   InterPro; IPR018499; Tetraspanin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   InterPro; IPR000301; Tetraspanin_subgr.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
DR   HOGENOMDNA; RAT2.PE1627; -.
KW   ENSRNOG00000017874820036002503210000011;
KW   Cd53; CD53_RAT; BC078900; M57276;
KW   Complete proteome; Direct protein sequencing; Glycoprotein; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   219 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGMSSLKLLK YVLFFFNFLF WVCGCCILGF GIHLLVQNTY GILFRNLPFL TLGNVLVIVG
     SIIMVVAFLG CMGSIKENKC LLMSFFVLLL LILLAEVTLA ILLFVYEKKI NTLVAEGLND
     SIQHYHSDNS TRMAWDFIQS QLQCCGVNGS SDWISGPPSS CPSGADVQGC YKKGQAWFHS
     NFLYIGIVTI CVCVIQVLGM SFALTLNCQI DKTSQALGL
//

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