(data stored in ACNUC4305 zone)

HOGENOM: RAT2_PE873

ID   RAT2_PE873                           STANDARD;      PRT;   202 AA.
AC   RAT2_PE873; Q9EQL5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Transmembrane 4 L6 family member 4; (RAT2.PE873).
GN   Name=Tm4sf4; Synonyms=Lrtm4;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT2.PE873.
CC       Rattus norvegicus chromosome 2 RGSC3.4  sequence 1..258207540
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:T4S4_RAT
CC   -!- FUNCTION: Regulates the adhesive and proliferative status of
CC       intestinal epithelial cells. Can mediate density-dependent cell
CC       proliferation (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By
CC       similarity).
CC   -!- TISSUE SPECIFICITY: Expressed in liver and testis. Up-regulated in
CC       regenerating liver after partial hepatectomy.
CC   -!- SIMILARITY: Belongs to the L6 tetraspanin family.
CC   -!- GENE_FAMILY: HOG000030899 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000016437;ENSRNOT00000022105;ENSRNOP00000022105.
DR   EMBL; AF205717; - ;
DR   EMBL; BC091131; - ;
DR   UniProtKB/Swiss-Prot; Q9EQL5; -.
DR   EMBL; AF205717; AAG35665.1; -; mRNA.
DR   EMBL; BC091131; AAH91131.1; -; mRNA.
DR   IPI; IPI00190125; -.
DR   RefSeq; NP_446237.1; NM_053785.1.
DR   UniGene; Rn.13425; -.
DR   Ensembl; ENSRNOT00000022105; ENSRNOP00000022105; ENSRNOG00000016437.
DR   GeneID; 116467; -.
DR   KEGG; rno:116467; -.
DR   UCSC; NM_053785; rat.
DR   CTD; 7104; -.
DR   RGD; 621784; Tm4sf4.
DR   eggNOG; roNOG05978; -.
DR   GeneTree; ENSGT00390000010992; -.
DR   InParanoid; Q9EQL5; -.
DR   OrthoDB; EOG46Q6TR; -.
DR   NextBio; 619006; -.
DR   Genevestigator; Q9EQL5; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042246; P:tissue regeneration; IEP:RGD.
DR   InterPro; IPR008661; L6_membrane.
DR   Pfam; PF05805; L6_membrane; 1.
DR   HOGENOMDNA; RAT2.PE873; -.
KW   ENSRNOG00000016437820036002503210000011;
KW   Tm4sf4; T4S4_RAT; AF205717; BC091131;
KW   Complete proteome; Glycoprotein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
SQ   SEQUENCE   202 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCTGGCARCL GGTLIPLAVF AVLANILLFF PGGKVVDDNS HLSDEVWYFG GILGSGVLMI
     FPALVFLGLQ NNDCCGCCGN ESCGKRFAMF TSTLFAVVGF LGAAYSFIVS AVSINKGPKC
     FMTNNTWGYP FHDGDYLNDQ ALWSKCEEPR DVVPWNLTLF SILLVIGGIQ MVLCAIQVIN
     GLLGTLCGDC QCCGCCGGDR PV
//

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