(data stored in ACNUC6288 zone)

HOGENOM: RAT6_PE201

ID   RAT6_PE201                           STANDARD;      PRT;   524 AA.
AC   RAT6_PE201; Q63186;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Translation initiation factor eIF-2B subunit delta;AltName:
DE   Full=eIF-2B GDP-GTP exchange factor subunit delta; (RAT6.PE201).
GN   Name=Eif2b4; Synonyms=Eif2bd;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT6.PE201.
CC       Rattus norvegicus chromosome 6 RGSC3.4  sequence 1..147636619 annotated
CC       by Ensembl
CC   -!- ANNOTATIONS ORIGIN:EI2BD_RAT
CC   -!- FUNCTION: Catalyzes the exchange of eukaryotic initiation factor
CC       2-bound GDP for GTP.
CC   -!- SUBUNIT: Complex of five different subunits; alpha, beta, gamma,
CC       delta and epsilon.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family.
CC   -!- GENE_FAMILY: HOG000176924 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000005301;ENSRNOT00000007763;ENSRNOP00000007763.
DR   EMBL; Z48225; - ;
DR   UniProtKB/Swiss-Prot; Q63186; -.
DR   EMBL; Z48225; CAA88256.1; -; mRNA.
DR   IPI; IPI00206019; -.
DR   PIR; S71961; S71961.
DR   RefSeq; NP_446402.1; NM_053950.1.
DR   UniGene; Rn.11060; -.
DR   ProteinModelPortal; Q63186; -.
DR   STRING; Q63186; -.
DR   PhosphoSite; Q63186; -.
DR   PRIDE; Q63186; -.
DR   Ensembl; ENSRNOT00000007763; ENSRNOP00000007763; ENSRNOG00000005301.
DR   GeneID; 117019; -.
DR   KEGG; rno:117019; -.
DR   UCSC; NM_053950; rat.
DR   CTD; 8890; -.
DR   RGD; 620208; Eif2b4.
DR   eggNOG; roNOG08745; -.
DR   GeneTree; ENSGT00550000075009; -.
DR   PhylomeDB; Q63186; -.
DR   NextBio; 619767; -.
DR   ArrayExpress; Q63186; -.
DR   Genevestigator; Q63186; -.
DR   GermOnline; ENSRNOG00000005301; Rattus norvegicus.
DR   GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.
DR   GO; GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.
DR   GO; GO:0031369; F:translation initiation factor binding; IDA:RGD.
DR   GO; GO:0042552; P:myelination; ISS:UniProtKB.
DR   GO; GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.
DR   GO; GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
DR   GO; GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.
DR   GO; GO:0009408; P:response to heat; IDA:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
DR   InterPro; IPR000649; IF-2B-related.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   HOGENOMDNA; RAT6.PE201; -.
KW   ENSRNOG00000005301820036002503210000011;
KW   Eif2b4; EI2BD_RAT; Z48225;
KW   Complete proteome; Initiation factor; Phosphoprotein;
KW   Protein biosynthesis; Reference proteome.
SQ   SEQUENCE   524 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI
     GSAVSAAQRQ DPVRELQGTG SQLGGTTGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG
     EQGGPSPQAC PSTAGEATSG VKRVPEHTQA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL
     FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLV SGSNARCIAL LHALQQVIQD
     YTTPPNEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF FNKEVTGMSS SKREEEAKSE
     LKEAIDRYVQ EKIVLASQAI SRFASKKISD GDVILVYGCS SLVSRILQEA WVEGRRFRVV
     VVDSRPRLEG RHMLHCLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG
     TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVTLANWQNN
     SSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ
//

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