(data stored in ACNUC25403 zone)

HOGENOM: RAT8_PE421

ID   RAT8_PE421                           STANDARD;      PRT;   392 AA.
AC   RAT8_PE421; P60572;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pannexin-3; (RAT8.PE421).
GN   Name=Panx3; Synonyms=Px3;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT8.PE421.
CC       Rattus norvegicus chromosome 8 RGSC3.4  sequence 1..129041809 annotated
CC       by Ensembl
CC   -!- ANNOTATIONS ORIGIN:PANX3_RAT
CC   -!- FUNCTION: Structural component of the gap junctions and the
CC       hemichannels.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Potential). Cell junction, gap junction.
CC   -!- TISSUE SPECIFICITY: Skin.
CC   -!- SIMILARITY: Belongs to the pannexin family.
CC   -!- GENE_FAMILY: HOG000063721 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000031675;ENSRNOT00000042717;ENSRNOP00000041185.
DR   EMBL; AJ557017; - ;
DR   UniProtKB/Swiss-Prot; P60572; -.
DR   EMBL; AJ557017; CAD89524.1; -; mRNA.
DR   IPI; IPI00409977; -.
DR   RefSeq; NP_955430.1; NM_199398.1.
DR   UniGene; Rn.77463; -.
DR   Ensembl; ENSRNOT00000042717; ENSRNOP00000041185; ENSRNOG00000031675.
DR   GeneID; 315567; -.
DR   KEGG; rno:315567; -.
DR   UCSC; NM_199398; rat.
DR   CTD; 116337; -.
DR   RGD; 735137; Panx3.
DR   eggNOG; roNOG04116; -.
DR   GeneTree; ENSGT00390000009703; -.
DR   InParanoid; P60572; -.
DR   OMA; MSLAFAQ; -.
DR   OrthoDB; EOG4R7V9Z; -.
DR   PhylomeDB; P60572; -.
DR   NextBio; 669428; -.
DR   ArrayExpress; P60572; -.
DR   Genevestigator; P60572; -.
DR   GermOnline; ENSRNOG00000031675; Rattus norvegicus.
DR   GO; GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055077; F:gap junction hemi-channel activity; ISS:UniProtKB.
DR   GO; GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; IMP:RGD.
DR   GO; GO:0034214; P:protein hexamerization; ISS:UniProtKB.
DR   InterPro; IPR000990; Innexin.
DR   Pfam; PF00876; Innexin; 1.
DR   PROSITE; PS51013; PANNEXIN; 1.
DR   HOGENOMDNA; RAT8.PE421; -.
KW   ENSRNOG00000031675820036002503210000011;
KW   Panx3; PANX3_RAT; AJ557017;
KW   Cell junction; Cell membrane; Complete proteome; Gap junction;
KW   Glycoprotein; Ion transport; Ionic channel; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   392 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLAHTAAEY MLSDALLPDR RGSRLKGLRL ELPLDKMVKF VTVGFPLLLM SLAFAQEFSS
     GSPISCFSPS NFSVRQAVFV DSSCWDSLAH YKQDEAGQYT VKSLWPHKAL PYSLLALAVA
     MYLPVLLWQY AAVPALSSDL LFIISELDKS YNRSIRLVQH MLKIRQKSSD PHVFWDELEK
     ARKERYFEFP LLERYLACKQ RSHWLVATYL LRNALLLLFT SATYLYLGHF HLDVFFQEEF
     SCSIKTGLLH EETHVPELIT CRLTSLSVFQ IVSVSSVAIY TVLVPVIIYN LTRLCRWDKR
     LLSIYEMLPA FDLLSRKMLG CPINDLNVIL LFLRANISEL ISFSWLSVLC VLKDTTTQKH
     NIDTVVDFMT LLAGLEPSKP KHLTQHTYDE HP
//

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