(data stored in SCRATCH3701 zone)

HOGENOM6: RHOE1_1_PE10

ID   RHOE1_1_PE10                         STANDARD;      PRT;   839 AA.
AC   RHOE1_1_PE10; E4WB70;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (RHOE1_1.PE10).
GN   Name=gyrA; OrderedLocusNames=REQ_00100;
OS   RHODOCOCCUS EQUI 103S.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Nocardiaceae; Rhodococcus.
OX   NCBI_TaxID=685727;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RHOE1_1.PE10.
CC       Rhodococcus equi 103S, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:E4WB70_RHOE1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4WB70; -.
DR   EMBL; FN563149; CBH46171.1; -; Genomic_DNA.
DR   RefSeq; YP_004004860.1; NC_014659.1.
DR   ProteinModelPortal; E4WB70; -.
DR   GeneID; 9967095; -.
DR   GenomeReviews; FN563149_GR; REQ_00100.
DR   KEGG; req:REQ_00100; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:2.120.10.30; 6-blade_b-propeller_TolB-like; 1.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RHOE1_1.PE10; -.
DR   PRODOM; RHOE1_1_PE10.
DR   SWISS-2DPAGE; RHOE1_1_PE10.
KW   DNA gyrase subunit a;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   839 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDTTLPPEE PSHDRIEPVD IQQEMQSSYI DYAMSVIVGR ALPDVRDGLK PVHRRVLYAM
     YDNGYRPDRG YVKSARPVAD TMGNYHPHGD SSIYDTLVRM AQPWSLRYPL VDGQGNFGSR
     GNDGAAAMRY TECRMTPLAM EMVREIDHDT VDFVPNYDGK TQEPTVLPSR IPNLLVNGSG
     GIAVGMATNI PPHNLREVAE AIYWALDNHE ADEEATLEAV MERVKGPDFP TSGLIVGGQG
     IQDAYRTGRG SIRMRGVVEI EESDRGSTQI VITELPYQVN PDNLITSIAE QVRDGKIAGI
     SKIEDQSSDR VGMRIVVVIK RDAVAKVVLN NLYKHSQLQT SFGANMLSIV DGVPRTLRLD
     QMIRYYVAHQ LEVIIRRTRY LLRKAEERAH ILRGLVKALD ALDEVIALIR SSQTVDVART
     GLMDLLTVDE IQADAILAMQ LRRLAALERQ KIIDELAEIE REIADLKDIL EKPERQRQIV
     KDELSEIVEK YGDDRRTRII AADGDVTDED LIAREDVVVT ITETGYAKRT RTDLYRSQKR
     GGKGVKGAEL KQEDIVKNFF VCSTHDWLLF FTTKGRVYRA KAYELPEANR TARGQHVANL
     LAFQPDEKIQ SIIHIKSYED APYLVLATRN GLVKKSRLAD FDSNRSGGIV AINLRDEDEL
     VGAVLCSSDD DLLLVSAKGQ SIRFAATDEA LRPMGRATSG VQGMRFNQDD ELLSLNVVRE
     GTYLLVATSG GYAKRTPIED YVAQGRGGKG VLTIQYDPKR GTLVGAVIVD DDDELYAITS
     GGGVIRTAAK QVRKAGRQTK GVRLMNLGEG DTLLAIARNA DEPEEGAAGA AGSDGAKES
//

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