(data stored in SCRATCH3701 zone)

HOGENOM6: RHOE4_4_PE10

ID   RHOE4_4_PE10                         STANDARD;      PRT;   843 AA.
AC   RHOE4_4_PE10; C0ZLF0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (RHOE4_4.PE10).
GN   Name=gyrA; OrderedLocusNames=RER_00100;
OS   RHODOCOCCUS ERYTHROPOLIS PR4.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Nocardiaceae; Rhodococcus.
OX   NCBI_TaxID=234621;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RHOE4_4.PE10.
CC       Rhodococcus erythropolis PR4, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C0ZLF0_RHOE4
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C0ZLF0; -.
DR   EMBL; AP008957; BAH30718.1; -; Genomic_DNA.
DR   RefSeq; YP_002763457.1; NC_012490.1.
DR   STRING; C0ZLF0; -.
DR   GeneID; 7713654; -.
DR   GenomeReviews; AP008957_GR; RER_00100.
DR   KEGG; rer:RER_00100; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:2.120.10.30; 6-blade_b-propeller_TolB-like; 1.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RHOE4_4.PE10; -.
DR   PRODOM; RHOE4_4_PE10.
DR   SWISS-2DPAGE; RHOE4_4_PE10.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   843 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDTTLPPDG PQHDRIEPVD IQQEMQNSYI DYAMSVIVGR ALPDVRDGLK PVHRRVLYAM
     YDNGYRPDRG YVKSARPVAE TMGNYHPHGD SSIYDTLVRM AQPWSLRYPL VDGQGNFGSR
     GNDGAAAMRY TECRLTPLAM EMLREIDHET VDFTPNYDGK TQEPTVLPSR IPNLLINGSN
     GIAVGMATNI PPHNLREVAE AIYWALENFE ADEEATLAAV MERIKGPDFP THGLIVGGQG
     IQDAYTTGRG SVRMRGVVEI EEDAKGRTTI VITELPYQVN PDNLITSIAE QVRDAKIGGI
     SDIHDESSDR VGMRIVVTVK RDAVAKVVLN NLYKHTQLQT SFGCNMLSIV DGVPRTLRLD
     QMIRLYTTHQ LEVIVRRTRY LLRKAQERAH ILRGLVKALD ALDEVIALIR ASQTVDIARA
     GLMELLDVDE IQADAILGMQ LRRLAALERQ KIVDELAEIE LEIADLEDIL ARPERQRAIV
     RDELKEIVDK YGDDRRTRII AADGDVNDED LIAREDVVVT ITETGYAKRT KTDLYRSQKR
     GGKGVQGAGL KQDDIVSHFF VTSTHDWLLF FTTKGRVYRA KAYELPEASR TARGQHVANL
     LAFQPDERIQ SVIQIKTYED APYLVLATRN GLVKKSKLTD FDSNRSGGIV AINLRGEDEL
     VGAVLCSADD DLLLVSAQGQ SIRFSATDEA LRPMGRATSG VQGMRFNGDD ELLSLNVVRE
     GTFLLVATSG GYSKRTGMED YPVQGRGGKG VLTIQYDKKR GTLVGALIVD DDDELYAITS
     GGGVIRTAAK QVRKAGRQTK GVRLMNLGEG DTLLAIARNA DEPEELAAET TDNADNADGA
     KES
//

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