(data stored in ACNUC30630 zone)

HOGENOM: RHOS4_4_PE586

ID   RHOS4_4_PE586                        STANDARD;      PRT;   503 AA.
AC   RHOS4_4_PE586; P95646; Q3J4Y0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Anthranilate synthase component 1; EC=4.1.3 27;AltName:
DE   Full=Anthranilate synthase component I; (RHOS4_4.PE586).
GN   Name=trpE; OrderedLocusNames=RHOS4_05860; ORFNames=RSP_2004;
OS   RHODOBACTER SPHAEROIDES 2.4.1.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=272943;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RHOS4_4.PE586.
CC       Rhodobacter sphaeroides 2.4.1 chromosome 1, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:TRPE_RHOS4
CC   -!- CATALYTIC ACTIVITY: Chorismate + L-glutamine = anthranilate +
CC       pyruvate + L-glutamate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 1/5.
CC   -!- SUBUNIT: Tetramer of two components I and two components II (By
CC       similarity).
CC   -!- MISCELLANEOUS: Component I catalyzes the formation of anthranilate
CC       using ammonia rather than glutamine, whereas component II provides
CC       glutamine amidotransferase activity.
CC   -!- SIMILARITY: Belongs to the anthranilate synthase component I
CC       family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA78154.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000025142 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P95646; Q3J4Y0; -.
DR   EMBL; Y09072; CAA70293.1; -; Genomic_DNA.
DR   EMBL; CP000143; ABA78154.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_352055.1; NC_007493.1.
DR   ProteinModelPortal; P95646; -.
DR   STRING; P95646; -.
DR   GeneID; 3719337; -.
DR   GenomeReviews; CP000143_GR; RHOS4_05860.
DR   KEGG; rsp:RSP_2004; -.
DR   NMPDR; fig|272943.3.peg.665; -.
DR   eggNOG; COG0147; -.
DR   PhylomeDB; P95646; -.
DR   ProtClustDB; PRK13573; -.
DR   BioCyc; RSPH272943:RSP_2004-MON; -.
DR   GO; GO:0004049; F:anthranilate synthase activity; IEA:EC.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR019999; Anth_synth_I.
DR   InterPro; IPR006805; Anth_synth_I_N.
DR   InterPro; IPR005256; Anth_synth_I_PabB.
DR   InterPro; IPR015890; Chorismate-bd_C.
DR   Gene3D; G3DSA:3.60.120.10; TRPE_1_chor_bd; 1.
DR   Pfam; PF04715; Anth_synt_I_N; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   PRINTS; PR00095; ANTSNTHASEI.
DR   SUPFAM; SSF56322; TRPE_1_chor_bd; 1.
DR   TIGRFAMs; TIGR00564; TrpE_most; 1.
DR   HOGENOMDNA; RHOS4_4.PE586; -.
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Lyase; Reference proteome; Tryptophan biosynthesis.
SQ   SEQUENCE   503 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLVTSFESF ERGWKAGQNQ IVYARLTADL DTPVSLMLKL AEARTDTFML ESVTGGEIRG
     RYSVVGMKPD LIWQCHGQDS RINREARFDR QAFQPLEGHP LETLRALIAE SRIEMPADLP
     PIAAGLFGYL GYDMIRLVEH LPGINPDPLG LPDAVLMRPS VVAVLDGVKG EVTVVAPAWV
     SSGLSARAAY AQAAERVMDA LRDLDRAPPA QRDFGEVAQV GEMRSNFTHE GYKAAVEKAK
     DYIRAGDIFQ VVPSQRWAQD FRLPPFALYR SLRKTNPSPF MFFFNFGGFQ VVGASPEILV
     RLRDREVTVR PIAGTRKRGA TPEEDRALEA DLLSDKKELA EHLMLLDLGR NDVGRVAKIG
     TVRPTEKFII ERYSHVMHIV SNVVGEIAEG EDALSALLAG LPAGTVSGAP KVRAMEIIDE
     LEPEKRGVYG GGVGYFAANG EMDFCIALRT AVLKDETLYI QSGGGVVYDS DPEAEYQETV
     NKARALRRAA EDAGLFARRA GNG
//

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