(data stored in SCRATCH3701 zone)

HOGENOM6: RICAE_1_PE219

ID   RICAE_1_PE219                        STANDARD;      PRT;   905 AA.
AC   RICAE_1_PE219; C3PMP7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (RICAE_1.PE219).
GN   Name=gyrA; OrderedLocusNames=RAF_ORF0253;
OS   RICKETTSIA AFRICAE ESF-5.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=347255;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RICAE_1.PE219.
CC       Rickettsia africae ESF-5 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C3PMP7_RICAE
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C3PMP7; -.
DR   EMBL; CP001612; ACP53207.1; -; Genomic_DNA.
DR   RefSeq; YP_002844950.1; NC_012633.1.
DR   STRING; C3PMP7; -.
DR   GeneID; 7815253; -.
DR   GenomeReviews; CP001612_GR; RAF_ORF0253.
DR   KEGG; raf:RAF_ORF0253; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RICAE_1.PE219; -.
DR   PRODOM; RICAE_1_PE219.
DR   SWISS-2DPAGE; RICAE_1_PE219.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   905 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDKSSSNLV PVNIEDEMKV SYLDYAMSVI VSRAIPDVRD GLKPVHRRII YSMHEAGNHA
     SKPYRKSARI VGDVMGKYHP HGDSAIYDAL VRMAQDFSLR LPLVDGQGNF GSMDGDAAAA
     MRYTESRMAK VSYKLVEDID KETVSFNPNY DGSEEEPSVL PAMFPNLLVN GSGGIAVGMA
     TNIPPHNLGE VIDACCLYID NNDIEILDLL EVVKGPDFPT GSMILGISGI RSAYLTGRGS
     IIMRGRAEIE NIDNSRQAII ITEIPYMVNK ARLVEKIAEM VKEKRIEGIS DLRDESNKNG
     VRIFIELKKD VVAEVVLNQI YACTQLQTSF GVIMLALKDG LPKVMNLKEV IAAFVSFREV
     VITNRTIYLL NKARDRAHIL LGLTIAVSNI DEIIRIIKAS NDPNAAKQEL MARQWEALNI
     LPLVKLVDDK AMLNEQGKCN FTEVQAKAIL EMRLQRLTAM EKNKLEEDLK NLITEITEYL
     NILGSRTRLL EILKEELIKV KEEFATPRLT SIEFGEFDQD IEDLIQREEM VVTVTLGGYI
     KRVPLSSYRA QKRGGKGRSG LSMRDEDITT QVFVGSTHTP MLFFSNIGQV YSLKLYKLPL
     SNPQGKGRPM VNILPLKANE HITNIMPLPE NQDERDNLNI MFATAKGNIR RSDLLDFTKL
     QSNGKIAIRL DEDDKLIDVK PCKEDEHILL ATKAGKALRF PVESLRVIKS RTSDGVRGMK
     LAKEDSVISM TVLKGISSTK EDRDAYLSVP WEQRLEIAKG EVFNPEELGV SLTAPAIVEM
     ANSEEFILTV TENGFGKRSS AYGYRITDRG GSGIINMDIN DKTGLVVGVM PVKMDDELML
     ITNSGKLIRC KLESVRITGR NTSGVILFKL DDGEKVVSVS LIAETAESEE DSELEEEGLE
     QSEEV
//

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