(data stored in SCRATCH9089 zone)

HOGENOM6: RICBR_1_PE1305

ID   RICBR_1_PE1305                       STANDARD;      PRT;   736 AA.
AC   RICBR_1_PE1305; Q1RGX8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (RICBR_1.PE1305).
GN   Name=parC; OrderedLocusNames=RBE_1305;
OS   RICKETTSIA BELLII RML369-C.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia.
OX   NCBI_TaxID=336407;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RICBR_1.PE1305.
CC       Rickettsia bellii RML369-C, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:PARC_RICBR
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule
CC       (By similarity).
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1RGX8; -.
DR   EMBL; CP000087; ABE05386.1; -; Genomic_DNA.
DR   RefSeq; YP_538475.1; NC_007940.1.
DR   ProteinModelPortal; Q1RGX8; -.
DR   STRING; Q1RGX8; -.
DR   GeneID; 3995522; -.
DR   GenomeReviews; CP000087_GR; RBE_1305.
DR   KEGG; rbe:RBE_1305; -.
DR   eggNOG; COG0188; -.
DR   OMA; HNAAELC; -.
DR   ProtClustDB; PRK05561; -.
DR   BioCyc; RBEL336407:RBE_1305-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 2.
DR   Pfam; PF03989; DNA_gyraseA_C; 3.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; RICBR_1.PE1305; -.
DR   PRODOM; RICBR_1_PE1305.
DR   SWISS-2DPAGE; RICBR_1_PE1305.
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Topoisomerase.
SQ   SEQUENCE   736 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKEAKIENID FGSALSERYL AYALSTIMSR SLPDVRDGLK PVHRRLLYAM LQLRLEPNSG
     YKKCARVVGD VIGKYHPHGD VAVYDTLVRL AQHFSLRYPL IDGQGNFGSI DGDNAAAMRY
     TESRMTEICT LLMEDIDKDT VDFRSTYDDS DLEPVIMPAS FPNLLANGSE GIAVGMATNI
     PPHNLHELCD ALMHLIDHPK AEISDIMNFI KGPDFPTGGI IIDKSDVITS AYMTGRGSFR
     VRARWEKEEL NYGVYQIVVT EIPYQVQKSK LIEQIAILLK DKKIPLVSNI RDESTDIIRL
     VIEPRDRSCD PQIVMESLFK LTNLESRIQL NMNVIGSNNV PKVMNILEVL QEFLSHRQNI
     ITRRSTYLLN KIKHRLEILE GLRIAYLNLD EIIKIIREED EPKAIMMQRF QLTEIQVEAI
     LNTRLRSLRK LEEQEIITEH SNLQKQQAIL EEILNNPKEL WKVVKKEIKA VQAKFGLNTT
     IGARRTSFEQ VTLTNQVVDI TAFITKEPIT IICSKMGWVR SLKGHNNDLS SIKYKEGDAE
     KFILEAYTTD KILIISSEGR FFTLLADNIS KGKGTGESIK LLVDIGNNDI TEILVYKPDH
     LLLLASSIGK GFVVNSNEVM AQTKSGKQIM NVPDGHTCIA CLPVNGDSVA CIGESRKLLV
     FNIDEIPEMK KGQGVTLQKF KNAKLLDIKI FNREDGLSWN SGGKVKLEKN IIAFLGKRGS
     TGKLPPMGFP KNNRFS
//

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