(data stored in SCRATCH3701 zone)

HOGENOM6: RICBR_1_PE794

ID   RICBR_1_PE794                        STANDARD;      PRT;   905 AA.
AC   RICBR_1_PE794; Q1RID9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (RICBR_1.PE794).
GN   Name=gyrA; OrderedLocusNames=RBE_0794;
OS   RICKETTSIA BELLII RML369-C.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia.
OX   NCBI_TaxID=336407;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RICBR_1.PE794.
CC       Rickettsia bellii RML369-C, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:GYRA_RICBR
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1RID9; -.
DR   EMBL; CP000087; ABE04875.1; -; Genomic_DNA.
DR   RefSeq; YP_537964.1; NC_007940.1.
DR   ProteinModelPortal; Q1RID9; -.
DR   SMR; Q1RID9; 31-512.
DR   STRING; Q1RID9; -.
DR   GeneID; 3995617; -.
DR   GenomeReviews; CP000087_GR; RBE_0794.
DR   KEGG; rbe:RBE_0794; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; RBEL336407:RBE_0794-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RICBR_1.PE794; -.
DR   PRODOM; RICBR_1_PE794.
DR   SWISS-2DPAGE; RICBR_1_PE794.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   905 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDNNSSNLV PVNIEDEMKV SYLDYAMSVI VSRAIPDVRD GLKPVHRRII YSMHEAGNHA
     NRAYRKSARI VGDVMGKYHP HGDSAIYDSL VRMAQDFSLR LPLVDGQGNF GSLDGDAAAA
     MRYTESRMAK VAHKLIEDID KETVSFNPNY DGSEEEPSVL PSMFPNLLVN GSGGIAVGMA
     TNIPPHNLGE VIDACCLYVD NNDIEILDLL EVVKGPDFPT SGIILGVNGI KSAYLTGRGS
     IAIRGRAEIE NLGNGRQAII ITEIPYMVNK ARLVEKIAEM VKEKRIEGIS DLRDESNKNG
     IRIYIELKKD IVAEVVLNQI YSCTQLQTSF GVIMLALKDG LPKVMNLKEV IAAFVSFREV
     VITNRTIYLL NKARDKAHIL LGLTIAVSNI DEIIRIIKAA SDPNAAKQEL MARSWDALNI
     LPLVKLVDDK AMLNEEGKCS FTEAQAKAIL EMRLQRLTAM EKNKLEEDLK NLATEITEYL
     NILGSRERLL EILKEELIKV KEEFATPRLT SIEFGEFDQD IEDLIQREEM VVTVTLGGYI
     KRVPLSSYRA QKRGGKGRSG LSMRDEDITT QVFVGSTHTP MLFFSNIGQV YSLKLYKLPL
     SNPQGKGRPM VNILPLKGDE HITNIMPLPE NQDEWDNLNI MFATAKGNIR RSDLLDFKKI
     QSNGKIAIRL DEDDKLIDVK PCKEDEHILL ATKSGKALRF PVESLRVIKS RTSDGVRGMR
     LAEDDSVISM TVLKGIKATR EERDAYLSVS WEKRLEIAKG EEFNSEELGV DLTAESILEM
     ANSEEFILTV TENGFGKRSS AYGYRITDRG GSGIINMDIN DKTGLVVGVM PVKMDDELML
     ITNSGKLIRC KLETVRITGR NTSGVTLFRL DDGEKVVSAS LIAESSDDNE EDSEFEEEVA
     EEGSE
//

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