(data stored in SCRATCH3701 zone)

HOGENOM6: RICCK_1_PE228

ID   RICCK_1_PE228                        STANDARD;      PRT;   894 AA.
AC   RICCK_1_PE228; A8EXU9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (RICCK_1.PE228).
GN   OrderedLocusNames=A1E_01185;
OS   RICKETTSIA CANADENSIS STR. MCKIEL.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=293613;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RICCK_1.PE228.
CC       Rickettsia canadensis str. McKiel, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A8EXU9_RICCK
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A8EXU9; -.
DR   EMBL; CP000409; ABV73182.1; -; Genomic_DNA.
DR   RefSeq; YP_001491967.1; NC_009879.1.
DR   ProteinModelPortal; A8EXU9; -.
DR   SMR; A8EXU9; 31-512.
DR   STRING; A8EXU9; -.
DR   GeneID; 5626171; -.
DR   GenomeReviews; CP000409_GR; A1E_01185.
DR   KEGG; rcm:A1E_01185; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; RCAN293613:A1E_01185-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RICCK_1.PE228; -.
DR   PRODOM; RICCK_1_PE228.
DR   SWISS-2DPAGE; RICCK_1_PE228.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   894 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDKYSSNLV PVNIEDEMKV SYLDYAMSVI VSRAIPDVRD GLKPVHRRII YSMYEAGNHA
     SKPYRKSARI VGDVMGKYHP HGDSAIYDSL VRMAQDFSLR LPLVDGQGNF GSMDGDAAAA
     MRYTESRMAK VSHKLVEDID KETVSFNPNY DGSEEEPSVL PAMFPNLLVN GSGGIAVGMA
     TNIPPHNLGE VIDACCLYID NNDIEILDLL EVVKGPDFPT GSMILGISGI RSAYLTGRGS
     IIMRGRAEIE NIGNSRQAII ITEIPYMVNK ARLVEKIAEM VKEKRIEGIS DLRDESNKNG
     VRIFIELKKD VEAEVVLNQI YACTQLQTSF GVIMLALKDG LPKVMNLKEV IAAFVSFREV
     VITNRTVYLL NKARDKAHIL LGLTIAVSNI DEIIRIIKAS NDPNTAKQEV MARKWNALNI
     LPLVKLVDDK AMLNEHGKCS FTEVQAKAVL EMRLQRLTAM EKNKLEEDLK TLATEISEYL
     NILGSRERLL KILKEELIKV KEEFATPRLT SIEFGEFDKD IEDLIQREEM VVTVTLGGYI
     KRVPLSSYRS QKRGGKGRSG LSMRDEDMTT QVFVGSTHTP MLFFSNIGKV YSLKLYKLPL
     SNPQGKGRPM VNILPLKENE HITNIMPLPE NQDEWDNLNI MFATAKGNIR RSDLLDFKKI
     QSNGKIAIRL DEDDKLIDVK PCKEDEHILL ATKAGKALRF PVESLRVIKS RTSDGVRGMK
     LAGDDSVISM TVLKGISSTK EDRDAYLSVS WEQRLEIAKG KSFNPEELGV SLTLDSILEM
     ANSEEFILTV TENGFGKRSS AYGYRITDRG GSGIINMDIN DKTGLVVGVM PVKMDDELML
     ITNNGKLIRC KLESVRITGR NTSGVILFKL DDGEKVVSVS LIADTSASEE DNEL
//

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