(data stored in SCRATCH3701 zone)

HOGENOM6: RIFEL1_1_PE1055

ID   RIFEL1_1_PE1055                      STANDARD;      PRT;   906 AA.
AC   RIFEL1_1_PE1055; Q4UKM1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (RIFEL1_1.PE1055).
GN   Name=gyrA; OrderedLocusNames=RF_1055;
OS   RICKETTSIA FELIS URRWXCAL2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RIFEL1_1.PE1055.
CC       Rickettsia felis URRWXCal2, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:GYRA_RICFE
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q4UKM1; -.
DR   EMBL; CP000053; AAY61906.1; -; Genomic_DNA.
DR   RefSeq; YP_247071.1; NC_007109.1.
DR   HSSP; O51396; 1SUU.
DR   ProteinModelPortal; Q4UKM1; -.
DR   SMR; Q4UKM1; 31-512.
DR   GeneID; 3400165; -.
DR   GenomeReviews; CP000053_GR; RF_1055.
DR   KEGG; rfe:RF_1055; -.
DR   NMPDR; fig|315456.3.peg.1055; -.
DR   OMA; EEYSAQG; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; RFEL315456:RF_1055-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RIFEL1_1.PE1055; -.
DR   PRODOM; RIFEL1_1_PE1055.
DR   SWISS-2DPAGE; RIFEL1_1_PE1055.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   906 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDQNFSNLV PVNIEDEMKV SYLDYAMSVI VSRAIPDVRD GLKPVHRRII YSMYEAGNHA
     SKPYRKSARI VGDVMGKYHP HGDSAIYDSL VRMAQDFSLR LPLVDGQGNF GSMDGDAAAA
     MRYTESRMAK VSHKLVEDID KETVSFNPNY DGSEEEPSVL PAMFPNLLVN GSGGIAVGMA
     TNIPPHNLGE VIDACCLYID NNDIEILDLL EVVKGPDFPT GSMILGISGI RSAYLTGRGS
     IIMRGRAEIE NIGNSRQAII ITEIPYMVNK ARLVEKIAEM VKEKRIEGIS DLRDESNKNG
     VRIFIELKKD VVVEVVLNQI YACTQLQTSF GVIMLALKDG LPKVMNLKEV IAAFVSFREV
     VITNRTIYLL NKARDRAHIL LGLTIAVSNI DEIIRIIKAS NNPNAAKQEL MARSWDALNI
     LPLVKLVDDK AMLNEQGKCS FTEVQAKAIL EMRLQRLTAM EKNKLEEDLK NLATEITEYL
     NILGSRTRLL EILKEELIKV KEEFATPRLT SIEFGEFDQD IEDLIQREEM VVTVTLGGYI
     KRVPLSSYRA QKRGGKGRSG LSMRDEDITT QVFVGSTHTP MLFFSNIGQV YSLKLYKLPL
     SNPQGKGRPM VNILPLKENE HITNIMPLPE NQDEWDNLNI MFATAKGNIR RSDLLDFKKI
     QSNGKIAIRL DEDDKLIDVK PCKEDEHILL ATKAGKALRF PVESLRVIKS RTSDGVRGMK
     LAKEDSVISM TVLKGISSTK EDRDAYLTVP WEKRLEIAKG EEFNLEELGV TLTADSILEM
     ANSEEFILTV TENGFGKRSS AYGYRITDRG GSGIINMDIN DKTGLVVGVM PVKMDDELML
     ITNSGKLIRC KLESVRITGR NTSGVILFKL DDGEKVVSVS LIAETSESEE DSELEEDLEQ
     AEEVYT
//

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