(data stored in SCRATCH9089 zone)

HOGENOM6: RIFEL1_1_PE107

ID   RIFEL1_1_PE107                       STANDARD;      PRT;   737 AA.
AC   RIFEL1_1_PE107; Q4UNA0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (RIFEL1_1.PE107).
GN   Name=parC; OrderedLocusNames=RF_0107;
OS   RICKETTSIA FELIS URRWXCAL2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RIFEL1_1.PE107.
CC       Rickettsia felis URRWXCal2, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:PARC_RICFE
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule
CC       (By similarity).
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q4UNA0; -.
DR   EMBL; CP000053; AAY60958.1; -; Genomic_DNA.
DR   RefSeq; YP_246123.1; NC_007109.1.
DR   ProteinModelPortal; Q4UNA0; -.
DR   GeneID; 3401076; -.
DR   GenomeReviews; CP000053_GR; RF_0107.
DR   KEGG; rfe:RF_0107; -.
DR   NMPDR; fig|315456.3.peg.626; -.
DR   OMA; HNAAELC; -.
DR   ProtClustDB; PRK05561; -.
DR   BioCyc; RFEL315456:RF_0107-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 2.
DR   Gene3D; G3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 3.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; RIFEL1_1.PE107; -.
DR   PRODOM; RIFEL1_1_PE107.
DR   SWISS-2DPAGE; RIFEL1_1_PE107.
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Topoisomerase.
SQ   SEQUENCE   737 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKEAKIENID FGNALSERYL AYALSTIMSR SLPDVRDGLK PVHRRLLYAM LQLRLEPNSG
     YKKCARVVGD VIGKYHPHGD VAVYDTLVRL AQHFSLRYPL IDGQGNFGSI DGDNAAAMRY
     TESRMTEICT LLMVDIEKDT VDFRPTYDDS DLEPVIMPAS FPNLLANGSE GIAVGMATNI
     PPHNLHELCD ALVHLIDHPK AEISDMMNFI KGPDFPTGGI IIDKAELINA AYSTGRGSFR
     MRSRWEKEEL SYGTYQIVVT EIPYQVQKSK LIEQIAILLK DKKIPLVSNI RDESTDIIRL
     VIEPRDRGCD PQIVMESLFK LTNLESRIQL NMNVIGSNNV PRVMNILEVL QEFLAHRQNI
     VTRRSTYLLN KIKHRLEILE GLRIAYLNLD EIIKIIREED EPKAIMMERF KLTEIQVEAI
     LNTRLRSLRK LEEQEIINEH SNLQKQQAIL EEILNNPKEL WKIVKKEIKA VQTKFGLNTV
     IGARRTSFEE VTLTNQVVDI TAFITKEPIT IICSKMGWVR SLKGHNTDLS TIKYKEGDAE
     KFIIEAYTTD KILIVSSEGR FFTLLADNIS KGKGTGESIK LLVDIGNNDI TNILVHKSDQ
     LLLLASSIGK GFLVNSNEVM AQTKTGKQIM NVPDGHTCIA CLPVNGDSIA CIGESRKLLV
     FNIDEIPEMK KGQGVTLQKF KNAKLLDIKI FNKEDGLSWN NNGKVKLEKN IIAFLGKRGS
     TGKLPPMGFH KNNRFSS
//

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