(data stored in SCRATCH3701 zone)

HOGENOM6: RITYP1_1_PE190

ID   RITYP1_1_PE190                       STANDARD;      PRT;   905 AA.
AC   RITYP1_1_PE190; Q68XG2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (RITYP1_1.PE190).
GN   Name=gyrA; OrderedLocusNames=RT0196;
OS   RICKETTSIA TYPHI STR. WILMINGTON.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RITYP1_1.PE190.
CC       Rickettsia typhi str. Wilmington, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:GYRA_RICTY
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q68XG2; -.
DR   EMBL; AE017197; AAU03680.1; -; Genomic_DNA.
DR   RefSeq; YP_067162.1; NC_006142.1.
DR   HSSP; O51396; 1SUU.
DR   ProteinModelPortal; Q68XG2; -.
DR   SMR; Q68XG2; 31-512.
DR   GeneID; 2958656; -.
DR   GenomeReviews; AE017197_GR; RT0196.
DR   KEGG; rty:RT0196; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; RTYP257363:RT0196-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; RITYP1_1.PE190; -.
DR   PRODOM; RITYP1_1_PE190.
DR   SWISS-2DPAGE; RITYP1_1_PE190.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   905 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDKYSSNLV PVNIEDEMKA SYLDYAMSVI VSRAIPDVRD GLKPVHRRII YSMYEAGNHA
     SKPYRKSARI VGDVMGKYHP HGDSAIYDSL VRMTQDFSLR LPLVDGQGNF GSMDGDAAAA
     MRYTESRMSK VAHKLVEDID KGTVSFNINY DGSEEEPSVL PAMFPNLLVN GSGGIAVGMA
     TNIPPHNLGE IIDACCLYID NNDIEILDLL EVVKGPDFPT GSMILGISGI RSAYLTGRGS
     IIMRGKAEIE NIGNSRQAII ITEIPYMVNK ARLVEKIAEM VKEKRIEGIS DLRDESNKNG
     VRIFIELKKD VVAEVVLNQI YACTQLQTNF GVIMLALKDG LPKVMNLKEV IAAFVSFREV
     VITNRTIYLL NKARDRAHIL LGLAIAISNI DEIIYIIKAS NDTNLAKQEL MDRQWEVLDI
     LPLIKLVDDK VMLNERGKLS FTEVQAKAIL EMKLQRLTAM EKNKLEQDLK HLATEIAEYL
     NILDSRTRLL EILKEELIKV KEEFAVPRLT AIEFGEFDQD IEDLIQREEM VVTVTLGGYI
     KRVPLSSYRS QKRGGKGRSG LSMRDEDITM QVFVGSTHTP MLFFSNIGKV YSLKLYKLPL
     SNPQGKGRPM VNILPLQENE HITNIMPLPE NQDEWDHLNI MFATAKGNIR RSDLLDFKKI
     QLNGKIAIRL DEDDKLIDVK PCKEDEHILL ATKAGKALRF PVESLRIIKS RISDGVRGMK
     LAKEDSVISM TVLKGINSTK EDRDAYLTVP WEKRLKIAKG EEFNLEALGV HLNADSILEM
     ANSEEFILTV TENGFGKRSS AYGYRITDRG GSGIINMDIN DKTGLVVGVM PVKMDDELML
     ITNSGKLIRC KLESVRITGR NTSGVILFKL DDDEKVVSVS LIAETSESGE DSELVEDGLE
     SAENM
//

If you have problems or comments...

PBIL Back to PBIL home page