(data stored in SCRATCH9089 zone)

HOGENOM6: RITYP1_1_PE61

ID   RITYP1_1_PE61                        STANDARD;      PRT;   737 AA.
AC   RITYP1_1_PE61; Q68XU1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (RITYP1_1.PE61).
GN   Name=parC; OrderedLocusNames=RT0065;
OS   RICKETTSIA TYPHI STR. WILMINGTON.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RITYP1_1.PE61.
CC       Rickettsia typhi str. Wilmington, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:PARC_RICTY
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule
CC       (By similarity).
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q68XU1; -.
DR   EMBL; AE017197; AAU03551.1; -; Genomic_DNA.
DR   RefSeq; YP_067033.1; NC_006142.1.
DR   ProteinModelPortal; Q68XU1; -.
DR   GeneID; 2958686; -.
DR   GenomeReviews; AE017197_GR; RT0065.
DR   KEGG; rty:RT0065; -.
DR   OMA; HNAAELC; -.
DR   ProtClustDB; PRK05561; -.
DR   BioCyc; RTYP257363:RT0065-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 2.
DR   Pfam; PF03989; DNA_gyraseA_C; 2.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; RITYP1_1.PE61; -.
DR   PRODOM; RITYP1_1_PE61.
DR   SWISS-2DPAGE; RITYP1_1_PE61.
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Topoisomerase.
SQ   SEQUENCE   737 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKEAKIENID FGNALSERYL AYALSTIMSR SLPDVRDGLK PVHRRLLYAM LQLRLEPNSG
     YKKCARVVGD VIGKYHPHGD VAVYDTLVRL AQHFSLRYPL IDGQGNFGSI DGDNAAAMRY
     TESRMTEICM LLMKDIDKDT VDFRSTYDDS DLEPVIMPAS FPNLLANGSE GIAVGMATNI
     PPHNLHELCD ALLYLIDNPQ AGVNDIMNFI KGPDFPTGGI IIDQTKVINA AYTTGRGSFR
     VRSRWEKEEL SYGTYQIVVT EIPYQVQKSK LIEQIAILLK DKKIPLISSI RDESTDIIRL
     VIEPRDRSCD PQIVMESLFK LTNLESRIQL NMNVIGSNNV PRVMNIVEIL QEFLVHRQNI
     ITRRSTYLLN KIKQRLEILK VLKIVYLNLD EIIEIIRRED EPKTIIMERF KISEIQVEVI
     LNTRLRALQK LEEHAIIDEH SNLQKQQAIL EKILKNHKEL WKIVKKEIKS VQTQFGLNTI
     IGARRTSFEE VDLTNQVIDI TAFITKEPIT IICSKMGWIR LLKGHNTDLS TIKYKEGDAE
     KFIIEAYTTD KILIISSKGR FFTLLADNIS KGKGTAVSIK LLVDIGNNDI TNILVYKPYQ
     LLLLASSIGK GFLVNSNEVI AQTKAGKQIM NIPEGYACIT CLPVNGNSIA CINESRRLLI
     FNINEIPEMK KGQGVVLQRF KNAKLLDIKI FNKEDGLSWN DGKKIQLEKN IVAFLGKRGS
     AGTLPPIGFP KNNRFSS
//

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