(data stored in SCRATCH3701 zone)

HOGENOM6: ROSDO_1_PE2519

ID   ROSDO_1_PE2519                       STANDARD;      PRT;   905 AA.
AC   ROSDO_1_PE2519; Q165T2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (ROSDO_1.PE2519).
GN   Name=gyrA; OrderedLocusNames=RD1_2726;
OS   ROSEOBACTER DENITRIFICANS OCH 114.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Roseobacter.
OX   NCBI_TaxID=375451;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ROSDO_1.PE2519.
CC       Roseobacter denitrificans OCh 114, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q165T2_ROSDO
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q165T2; -.
DR   EMBL; CP000362; ABG32261.1; -; Genomic_DNA.
DR   RefSeq; YP_682947.1; NC_008209.1.
DR   ProteinModelPortal; Q165T2; -.
DR   SMR; Q165T2; 32-514.
DR   STRING; Q165T2; -.
DR   GeneID; 4196081; -.
DR   GenomeReviews; CP000362_GR; RD1_2726.
DR   KEGG; rde:RD1_2726; -.
DR   NMPDR; fig|375451.6.peg.2526; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; RDEN375451:RD1_2726-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ROSDO_1.PE2519; -.
DR   PRODOM; ROSDO_1_PE2519.
DR   SWISS-2DPAGE; ROSDO_1_PE2519.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   905 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRPERPVYDG PSVSIEQEMR TSYLDYAMSV IVSRAIPDLR DGLKPVHRRI LFAMHETGNT
     HDKPYRKSAR PVGDVMGQYH PHGDSAIYDA LVRMAQDFSM SLPLLDGQGN FGSMDGDNPA
     AMRYTEVRMD KPAAYLLADI DKDTVDFQDN YDGKQKEPTV LPARFPNMLV NGAGGIAVGM
     ATNIPPHNLG EVIDATLALI EEPDLTSEQL IDYVPGPDFP TGGIMLGRGG ARKAYLEGRG
     SVIIRAKTRV EEIRKDRWAI IVDEIPYQVN KATMIEKIAE QVREKKIDGI AHVQDESDRN
     GVRVVIELKR DATAEVVMNQ LYRFTPLQTY FGCNMLALNG GRPEQLTLRK FLTYFIDFRE
     DVVARRTAYL LRKARERSHV LCGLAVAVTN IDEVVATIRA SADAAEAREK LMTRRWPAQD
     ILPYIALIDD PTHTANDDGT YNLSETQARA ILDLRLQRLT QIGVKEVTDE LEELAGKIKE
     YLEILGSRDR IMGIIADELR EVRELFAVPR RTEIVDWSGD MEDEDLIARE DMVVTVTQGG
     YIKRTPLADF RSQRRGGKGL SGGSLKEDDV VTTLFVANTH TQLLFFTTDG MAYKLKTWRL
     PQGARTSKGK AIVNILPIPQ GVSIAAILPI DRDEKDWSQL QIVFATSAGT VRRNALSDFT
     NVKSNGKIAM KFEDEHAETT LINARIASPD DDVMLVTASG RAIRFPSEDV RVFNSRSSVG
     VRGVKLSGHD KVVSMSVIRH FDATADERAA YLKMRRAMVG LTDDSETSDE DETSANATIS
     PDRYAEMSAA ENLILTLTAG GAGKLSSSHD YPVRGRGGMG VTAWDKRMQT GQIVASFPVE
     MDDQIMLATS KGQSIRVPVE GISFRSRSAG GVKVFNTGKG EEVVSVAWIA DQGEDDTDGE
     DAQNA
//

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