(data stored in ACNUC7421 zone)

HOGENOM: SACEN_1_PE1

ID   SACEN_1_PE1                          STANDARD;      PRT;   592 AA.
AC   SACEN_1_PE1; A4F5N2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (SACEN_1.PE1).
GN   Name=dnaA; OrderedLocusNames=SACE_0001;
OS   SACCHAROPOLYSPORA ERYTHRAEA NRRL 2338.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Pseudonocardineae; Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=405948;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SACEN_1.PE1.
CC       Saccharopolyspora erythraea NRRL 2338 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:A4F5N2_SACEN
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A4F5N2; -.
DR   EMBL; AM420293; CAL99356.1; -; Genomic_DNA.
DR   RefSeq; YP_001102282.1; NC_009142.1.
DR   ProteinModelPortal; A4F5N2; -.
DR   STRING; A4F5N2; -.
DR   GeneID; 4947128; -.
DR   GenomeReviews; AM420293_GR; SACE_0001.
DR   KEGG; sen:SACE_0001; -.
DR   eggNOG; COG0593; -.
DR   OMA; VAFQRRY; -.
DR   PhylomeDB; A4F5N2; -.
DR   ProtClustDB; PRK00149; -.
DR   BioCyc; SERY405948:SACE_0001-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; SACEN_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   592 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADHQADLGR VWEEVVQELS SGTLSPQQRA WMRVTRPIGL LDGTALLAAP SDFAKEAIER
     ALREPITDAL SRRLGRDVSL AVKVDTAVQA PSRPAPPPAE SWPTRDSITG PDRPTGFAEA
     GVSPYISTSS SYLQPPRTDS FTPPVTGSLP AVDNHYPTAE QPRVVDYQSA DYPTTEYHDW
     PTAAELTAGT PHEGESEAAP ESDDEVDEER EAIDAANEIW PTFGRGQAPE AQQGQPFTAP
     KHAPPTSQTR LNAKYTFDTF VIGASNRFAH AAAVAAAEAP ARAYNPLFIW GESGLGKTHL
     LHAVGHYAQR LFPGMRVRYV STEEFTNDFI NSLRDDRQVA FQRRYRDVDV LLVDDIQFLE
     GKEGTQEEFF HTFNTLHNSN KQIVVSSDRP PKGLRTLEDR LRTRFEWGLI TDIQPPELET
     RIAILRKKAA QDRMNAPADV LEFIAARIER NIRELEGALI RVTAFASLNR QPVDVQLAEI
     VLRDLIPDSQ TPEITAPTIM AVTADFFSVT IDDLCGPGKT KALAQARQIA MYLCRELTDS
     SLPKIGQSFG GRDHTTVMHA DKKIRKEMAE RRRVYDQVQE LTSRIKQQSR GS
//

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