(data stored in SCRATCH9089 zone)

HOGENOM6: SAENT1_1_PE3063

ID   SAENT1_1_PE3063                      STANDARD;      PRT;   752 AA.
AC   SAENT1_1_PE3063; P26973;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (SAENT1_1.PE3063).
GN   Name=parC; OrderedLocusNames=STM3174;
OS   SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM STR. LT2.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SAENT1_1.PE3063.
CC       Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
CC       chromosome, complete genome.
CC   -!- ANNOTATIONS ORIGIN:PARC_SALTY
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule.
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P26973; -.
DR   EMBL; M68936; AAA27180.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL22048.1; -; Genomic_DNA.
DR   PIR; A45582; A45582.
DR   RefSeq; NP_462089.1; NC_003197.1.
DR   ProteinModelPortal; P26973; -.
DR   SMR; P26973; 28-740.
DR   PRIDE; P26973; -.
DR   GeneID; 1254697; -.
DR   GenomeReviews; AE006468_GR; STM3174.
DR   KEGG; stm:STM3174; -.
DR   NMPDR; fig|99287.1.peg.3065; -.
DR   OMA; ILAITNE; -.
DR   ProtClustDB; PRK05561; -.
DR   BioCyc; STYP99287:STM3174-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 2.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; SAENT1_1.PE3063; -.
DR   PRODOM; SAENT1_1_PE3063.
DR   SWISS-2DPAGE; SAENT1_1_PE3063.
KW   DNA topoisomerase IV subunit A;
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Reference proteome; Topoisomerase.
SQ   SEQUENCE   752 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNATAKF
     KKSARTVGDV LGKYHPHGDS ACYEAMVLMA QPFSYRYPLV DGQGNWGAPD DPKSFAAMRY
     TESRLSKYAE LLLSELGQGT ADWVPNFDGT MQEPKMLPAR LPNILLNGTT GIAVGMATDI
     PPHNLREVAK AAITLIEQPK TTLDQLLDIV QGPDYPTEAE IITPRAEIRK IYENGRGSVR
     MRAVWTKEDG AVVISALPHQ VSGAKVLEQI AAQMRNKKLP MVDDLRDESD HENPTRLVIV
     PRSNRVDMEQ VMNHLFATTD LEKSYRINLN MIGLDGRPAV KNLLEILTEW LAFRRDTVRR
     RLNYRLEKVL KRLHILEGLL VAFLNIDEVI EIIRSEDEPK PALMSRFGIS ETQAEAILEL
     KLRHLAKLEE MKIRGEQDEL EKERDQLQGI LASERKMNTL LKKELQADAD AYGDDRRSPL
     REREEAKAMS EHDMLPSEPV TIVLSQMGWV RSAKGHDIDA PGLNYKAGDS FKAAVKGKSN
     QPVVFIDTTG RSYAIDPITL PSARGQGEPL TGKLTLPPGA TVEHMLMEGD DQKLLMASDA
     GYGFVCTFND LVARNRAGKT LITLPENAHV MPPLVIEDEH DMLLAITQAG RMLMFPVDSL
     PQLSKGKGNK IINIPSAEAA KGDDGLAHLY VLPPQSTLTI HVGKRKIKLR PEELQKVVGE
     RGRRGTLMRG LQRIDRIEID SPHRVSHGDS EE
//

If you have problems or comments...

PBIL Back to PBIL home page