(data stored in SCRATCH zone)

HOGENOM: SAENT4_1_PE1004

ID   SAENT4_1_PE1004                      STANDARD;      PRT;   577 AA.
AC   SAENT4_1_PE1004; Q5PN10;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cell volume regulation protein A; (SAENT4_1.PE1004).
GN   Name=cvrA; OrderedLocusNames=SPA1072;
OS   SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR PARATYPHI A STR. ATCC 9150.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SAENT4_1.PE1004.
CC       Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
CC       chromosome, complete genome.
CC   -!- ANNOTATIONS ORIGIN:CVRA_SALPA
CC   -!- FUNCTION: Participates in control of cell volume in low-osmolarity
CC       conditions (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (Potential).
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 1
CC       (CPA1) transporter (TC 2.A.36) family. CvrA subfamily.
CC   -!- SIMILARITY: Contains 1 RCK C-terminal domain.
CC   -!- GENE_FAMILY: HOG000019567 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5PN10; -.
DR   EMBL; CP000026; AAV77043.1; -; Genomic_DNA.
DR   RefSeq; YP_150355.1; NC_006511.1.
DR   ProteinModelPortal; Q5PN10; -.
DR   PRIDE; Q5PN10; -.
DR   GeneID; 3178457; -.
DR   GenomeReviews; CP000026_GR; SPA1072.
DR   KEGG; spt:SPA1072; -.
DR   OMA; SEWELFV; -.
DR   ProtClustDB; PRK05326; -.
DR   BioCyc; SENT295319:SPA1072-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   HAMAP; MF_01075; CvrA; 1; -.
DR   InterPro; IPR018421; Cation/H_exchang_CvrA_bac.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR   InterPro; IPR016169; CO_DH_flavot_FAD-bd_sub2.
DR   InterPro; IPR023729; CvrA.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Gene3D; G3DSA:3.30.465.10; CO_DH_flavoprot_FAD-bd_sub2; 1.
DR   PANTHER; PTHR10110:SF7; Cation/H_exchang_CvrA_cons-reg; 1.
DR   PANTHER; PTHR10110; Cation/H_exchanger_cons-reg; 1.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02080; TrkA_C; 1.
DR   PROSITE; PS51202; RCK_C; 1.
DR   HOGENOMDNA; SAENT4_1.PE1004; -.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   577 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDAATIISLF ILGSILVTSS ILLSSFSSRL GIPILVIFLA IGMLAGVDGI GGIPFDNYPF
     AYMVSNLALA IILLDGGMRT QASSFRVALG PALSLATLGV LITSGLTGMM AAWLFHLDLI
     EGLLIGAIVG STDAAAVFSL LGGKGLNERV GSTLEIESGS NDPMAVFLTI TLIEMIQKHE
     TGLDWMFAVH IIQQFGLGIV FGLGGGYLLQ QMINRISLPS GLYPMLALSG GILIFALTTA
     LEGSGILAVY LCGFLLGNRP IRNRYGILQN FDGLAWLAQI AMFLVLGLLV TPSDLWPIAV
     PALILSIWMI FFARPLSVFT GLLPFRGFNL RERIFISWVG LRGAVPIILA VFPMMAGLEN
     ARLFFNVAFF VVLVSLLLQG TSLSWAAKRA KVVVPPVGWP VSRVGLDIHP DNPWEQFIYQ
     LSADKWCVGA ALRDLHMPNE TRIAALFRNN ELFHPTGSTR LQEGDVLCVI GRERDLPALG
     KLFSQSPPVS LDQRFFGDFI LEANAKFADV ALIYGLEEGT EYRDKQQTLG EIIQQLLGAA
     PVVGDQVEFG GMIWTVAEKE DNVVRKIGVR VAEDEAE
//

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