(data stored in SCRATCH zone)

HOGENOM: SAENT6_1_PE1003

ID   SAENT6_1_PE1003                      STANDARD;      PRT;   173 AA.
AC   SAENT6_1_PE1003; A9MND5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Crossover junction endodeoxyribonuclease ruvC; EC=3.1.22
DE   4;AltName: Full=Holliday junction nuclease ruvC;AltName: Full=Holliday
DE   junction resolvase ruvC; (SAENT6_1.PE1003).
GN   Name=ruvC; OrderedLocusNames=SARI_01050;
OS   SALMONELLA ENTERICA SUBSP. ARIZONAE SEROVAR 62:Z4,Z23:-- STR. RSK2980.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella; Salmonella enterica subsp. arizonae
OC   serovar 62:z4,z23:--.
OX   NCBI_TaxID=882884;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SAENT6_1.PE1003.
CC       Salmonella enterica subsp. arizonae serovar 62:z4,z23:-- str. RSK2980
CC       chromosome, complete genome.
CC   -!- ANNOTATIONS ORIGIN:RUVC_SALAR
CC   -!- FUNCTION: Nuclease that resolves Holliday junction intermediates
CC       in genetic recombination. Cleaves the cruciform structure in
CC       supercoiled DNA by nicking to strands with the same polarity at
CC       sites symmetrically opposed at the junction in the homologous arms
CC       and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl
CC       group (By similarity).
CC   -!- CATALYTIC ACTIVITY: Endonucleolytic cleavage at a junction such as
CC       a reciprocal single-stranded crossover between two homologous DNA
CC       duplexes (Holliday junction).
CC   -!- COFACTOR: Binds 1 magnesium ion per subunit (By similarity).
CC   -!- SIMILARITY: Belongs to the ruvC family.
CC   -!- GENE_FAMILY: HOG000012181 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A9MND5; -.
DR   EMBL; CP000880; ABX20958.1; -; Genomic_DNA.
DR   RefSeq; YP_001570100.1; NC_010067.1.
DR   ProteinModelPortal; A9MND5; -.
DR   SMR; A9MND5; 2-159.
DR   STRING; A9MND5; -.
DR   GeneID; 5760319; -.
DR   GenomeReviews; CP000880_GR; SARI_01050.
DR   KEGG; ses:SARI_01050; -.
DR   OMA; GRADKKQ; -.
DR   ProtClustDB; PRK00039; -.
DR   GO; GO:0008821; F:crossover junction endodeoxyribonuclease activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   HAMAP; MF_00034; RuvC; 1; -.
DR   InterPro; IPR012337; RNaseH-like.
DR   InterPro; IPR020563; X-over_junc_endoDNase_Mg_BS.
DR   InterPro; IPR002176; X-over_junc_endoDNase_RuvC.
DR   Pfam; PF02075; RuvC; 1.
DR   PRINTS; PR00696; RSOLVASERUVC.
DR   SUPFAM; SSF53098; RNaseH_fold; 1.
DR   TIGRFAMs; TIGR00228; RuvC; 1.
DR   PROSITE; PS01321; RUVC; 1.
DR   HOGENOMDNA; SAENT6_1.PE1003; -.
KW   Holliday junction resolvase;
KW   Complete proteome; DNA damage; DNA recombination; DNA repair;
KW   Hydrolase; Magnesium; Metal-binding; Nuclease.
SQ   SEQUENCE   173 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAIILGIDPG SRITGYGVIR QVGRQLTYLG SGCIRTKVDD LPSRLKLIYA GVTEIITQFQ
     PDYFAIEQVF MAKNADSALK LGQARGVAIV AAVNRELPVF EYAARQVKQT VVGIGSAEKS
     QVQHMVRTLL KLPANPQADA ADALAIAITH CHVSQNAMQM SESRLNLARG RLR
//

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