(data stored in ACNUC27125 zone)

HOGENOM: SCHPO_2_PE1131

ID   SCHPO_2_PE1131                       STANDARD;      PRT;   554 AA.
AC   SCHPO_2_PE1131; Q12705; Q9P7E4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit;
DE   EC=3.1.3 16; (SCHPO_2.PE1131).
GN   Name=ppb1; ORFNames=SPBP4H10.04, SPBC1346.01c;
OS   SCHIZOSACCHAROMYCES POMBE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SCHPO_2.PE1131.
CC       Schizosaccharomyces pombe chromosome II EF1 full sequence 1..4539804
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:PP2B_SCHPO
CC   -!- FUNCTION: Calcium-dependent, calmodulin-stimulated protein
CC       phosphatase. This subunit may have a role in the calmodulin
CC       activation of calcineurin. Appears to be involved in cytokinesis,
CC       mating, transport, nuclear and spindle pole body positioning, and
CC       cell shape.
CC   -!- CATALYTIC ACTIVITY: A phosphoprotein + H(2)O = a protein +
CC       phosphate.
CC   -!- COFACTOR: Binds 1 Fe(3+) ion per subunit (By similarity).
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- SUBUNIT: Composed of two components (A and B), the A component is
CC       the catalytic subunit and the B component confers calcium
CC       sensitivity.
CC   -!- SIMILARITY: Belongs to the PPP phosphatase family. PP-2B
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000172699 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Schizosaccharomyces_pombe;SPBP4H10.04;SPBP4H10.04-1;SPBP4H10.04-1.
DR   UniProtKB/Swiss-Prot; Q12705; Q9P7E4; -.
DR   EMBL; D28955; BAA06081.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAB83162.1; -; Genomic_DNA.
DR   PIR; T45137; T45137.
DR   PIR; T50310; T50310.
DR   RefSeq; NP_596178.1; NM_001022097.1.
DR   ProteinModelPortal; Q12705; -.
DR   SMR; Q12705; 38-401.
DR   IntAct; Q12705; 1.
DR   STRING; Q12705; -.
DR   EnsemblFungi; SPBP4H10.04-1; SPBP4H10.04-1; SPBP4H10.04.
DR   GeneID; 2540024; -.
DR   GenomeReviews; CU329671_GR; ppb1.
DR   KEGG; spo:SPBP4H10.04; -.
DR   NMPDR; fig|4896.1.peg.2044; -.
DR   GeneDB_Spombe; SPBP4H10.04; -.
DR   eggNOG; fuNOG05461; -.
DR   GeneTree; EFGT00050000001947; -.
DR   OMA; TIQTFEE; -.
DR   OrthoDB; EOG45XC4G; -.
DR   PhylomeDB; Q12705; -.
DR   BioCyc; SPOM-XXX-01:SPOM-XXX-01-004209-MON; -.
DR   ArrayExpress; Q12705; -.
DR   GO; GO:0032153; C:cell division site; IDA:GeneDB_Spombe.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_Spombe.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IMP:GeneDB_Spombe.
DR   GO; GO:0019722; P:calcium-mediated signaling; IMP:GeneDB_Spombe.
DR   GO; GO:0030644; P:cellular chloride ion homeostasis; TAS:GeneDB_Spombe.
DR   GO; GO:0031505; P:fungal-type cell wall organization; IGI:GeneDB_Spombe.
DR   GO; GO:0071775; P:regulation of cell cycle cytokinesis; IMP:GeneDB_Spombe.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0031137; P:regulation of conjugation with cellular fusion; IMP:GeneDB_Spombe.
DR   GO; GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:GeneDB_Spombe.
DR   GO; GO:0070631; P:spindle pole body localization; IMP:GeneDB_Spombe.
DR   InterPro; IPR004843; Metallo_PEstase_dom.
DR   InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR   Pfam; PF00149; Metallophos; 1.
DR   PRINTS; PR00114; STPHPHTASE.
DR   SMART; SM00156; PP2Ac; 1.
DR   PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
DR   HOGENOMDNA; SCHPO_2.PE1131; -.
KW   SPBP4H10.047cc7236820036002503210000011;
KW   Q12705;
KW   Calmodulin-binding; Cell shape; Complete proteome; Hydrolase; Iron;
KW   Manganese; Metal-binding; Protein phosphatase; Reference proteome;
KW   Zinc.
SQ   SEQUENCE   554 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTSGPHNLED PIVRAIRQKN QAPSHDFTIF VQEDGSSVST LDRVVKNVQA PATYIPTDVE
     FFDINEPDKP DLHFLRNHFI REGRLSEEQT LYIIKKATEI LKSEDNLIEV DAPVTVCGDI
     HGQYYDLMKL FEVGGNPANT QYLFLGDYVD RGYFSIECLL YLWALKIWYP KTLWLLRGNH
     ECAHLTDYFT FKLECTHKYN IKVYEACLQS FNALPLAAIM NKQFLCVHGG LSPELHTLND
     IRMINRFCEP PTHGLMCDLL WSDPLEDFGS EKSNKHFIHN NVRGCSYFYS YQAVCTFLEN
     NNLLSVIRAH EAQDVGYRMY RKTKTTGFPS LMTIFSAPNY LDVYNNKAAV LKYENNVMNI
     RQFNCSPHPY WLPNFMDVFT WSLPFVGEKV SEMLISMLNI CSKEELYETD LKESAPTQHK
     QPAPSENENK ADQEIDIEAR RQIIKNKIMA IGRISRVFSV LREERESVSE LKNVSGTQRL
     PAGTLMLGAE GIKNAINSFD DARKLDIQNE RLPPSNSRRR STDLKAFEEV MNSSEDDTSI
     DHLVERFADK KSSL
//

If you have problems or comments...

PBIL Back to PBIL home page