(data stored in ACNUC4362 zone)

HOGENOM: SCHPO_2_PE1155

ID   SCHPO_2_PE1155                       STANDARD;      PRT;   615 AA.
AC   SCHPO_2_PE1155; Q9P7W3; P78844;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable ATP-citrate synthase subunit 1; EC=2.3.3
DE   8;AltName: Full=ATP-citrate (SCHPO_2.PE1155) (pro-S-)-lyase 1;AltName:
DE   Full=Citrate cleavage enzyme subunit 1; .
GN   ORFNames=SPBC1703.07;
OS   SCHIZOSACCHAROMYCES POMBE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SCHPO_2.PE1155.
CC       Schizosaccharomyces pombe chromosome II EF1 full sequence 1..4539804
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:ACL1_SCHPO
CC   -!- FUNCTION: Catalyzes the formation of cytosolic acetyl-CoA, which
CC       is mainly used for the biosynthesis of fatty acids and sterols (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ADP + phosphate + acetyl-CoA + oxaloacetate =
CC       ATP + citrate + CoA.
CC   -!- SUBUNIT: Composed of two subunits (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the succinate/malate CoA ligase alpha
CC       subunit family.
CC   -!- GENE_FAMILY: HOG000151479 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Schizosaccharomyces_pombe;SPBC1703.07;SPBC1703.07-1;SPBC1703.07-1.
DR   UniProtKB/Swiss-Prot; Q9P7W3; P78844; -.
DR   EMBL; CU329671; CAB66451.1; -; Genomic_DNA.
DR   EMBL; D89194; BAA13855.1; -; mRNA.
DR   PIR; T42753; T42753.
DR   PIR; T50320; T50320.
DR   RefSeq; NP_596202.1; NM_001022121.1.
DR   ProteinModelPortal; Q9P7W3; -.
DR   STRING; Q9P7W3; -.
DR   EnsemblFungi; SPBC1703.07-1; SPBC1703.07-1; SPBC1703.07.
DR   GeneID; 2539879; -.
DR   KEGG; spo:SPBC1703.07; -.
DR   NMPDR; fig|4896.1.peg.2068; -.
DR   GeneDB_Spombe; SPBC1703.07; -.
DR   eggNOG; fuNOG06879; -.
DR   GeneTree; EFGT00050000003524; -.
DR   OMA; NVDGTIG; -.
DR   OrthoDB; EOG4CC78H; -.
DR   PhylomeDB; Q9P7W3; -.
DR   BioCyc; SPOM-XXX-01:SPOM-XXX-01-004232-MON; -.
DR   ArrayExpress; Q9P7W3; -.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_Spombe.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB_Spombe.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003878; F:ATP citrate synthase activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR   InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR   InterPro; IPR002020; Citrate_synthase-like.
DR   InterPro; IPR016141; Citrate_synthase-like_core.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR005810; CoA_lig_alpha.
DR   InterPro; IPR005811; CoA_ligase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR017866; Succ-CoA_synthase_bsu_CS.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   Gene3D; G3DSA:1.10.580.10; Citrate_synthase_lrg_a-sub; 1.
DR   Gene3D; G3DSA:1.10.230.10; Citrate_synthase_sm_a-sub; 1.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:3.40.50.261; Succinyl-CoA_synth-like; 1.
DR   Pfam; PF00285; Citrate_synt; 1.
DR   Pfam; PF02629; CoA_binding; 1.
DR   Pfam; PF00549; Ligase_CoA; 1.
DR   SUPFAM; SSF48256; Citrate_synthase_core; 1.
DR   PROSITE; PS01216; SUCCINYL_COA_LIG_1; 1.
DR   PROSITE; PS00399; SUCCINYL_COA_LIG_2; FALSE_NEG.
DR   PROSITE; PS01217; SUCCINYL_COA_LIG_3; 1.
DR   HOGENOMDNA; SCHPO_2.PE1155; -.
KW   SPBC1703.07ccc7236820036002503210000011;
KW   Q9P7W3;
KW   ATP-binding; Complete proteome; Cytoplasm; Lipid synthesis; Magnesium;
KW   Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome;
KW   Transferase.
SQ   SEQUENCE   615 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAGSVDKPSY ELFSKDTRAF VYGMQTKAVQ GMLDFDYMCG RTVPSVAAII YTFGSQSISK
     LYWGTKEILL PVYRTIEEAC TKHPEVDVVV NFASSRSAYA STMELMEFPQ IRCIAIIAEG
     VPERRAREIL VTSKEKNVVI IGPATVGGIK PGCFKIGNTG GMMDNIVASK LYRPGSVAYV
     SKSGGMSNEL NNIISHTTDG VYEGIAIGGD RYPGTTFIDH LIRFEADPAC KLMVLLGEVG
     GVEEYRVIEA VKNGTIKKPI VAWAIGTCSS MFKTEVQFGH AGSFANSELE TAVAKNQAMR
     EAGIYVPETF EKLPALLQEV YEGLVKKGVI VPQPEVAPPN IPLDYAWAKE LGLVRKPSSF
     ICTISNDRGS ELTYNNVPIS KVFEEELGIG GVISLLWLRR RLPSYATKFL EMVLQLTADH
     GPCVSGAMNT IITTRAGKDL ISSLVAGLLT IGTRFGGALD GAAQEFSKAY DAGLSPRAFV
     DSCRKANKLI PGIGHRIKSR NNPDLRVELV KGYVKKNFPS TKLLDYALAV ENVTTSKKDN
     LILNVDGCIA VCFVDLLRNC GAFTLEEANE YINLGILNGM FVLGRSIGLI GHHLDQKRLR
     APLYRHPWDD FLYLS
//

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