(data stored in ACNUC22857 zone)

HOGENOM: SCHPO_2_PE1384

ID   SCHPO_2_PE1384                       STANDARD;      PRT;   677 AA.
AC   SCHPO_2_PE1384; O43005;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=AP-2 complex subunit beta;AltName:
DE   Full=Beta-2-adaptin;AltName: Full=Beta-adaptin;AltName: Full=Clathrin
DE   assembly protein complex 2 beta large chain;AltName: Full=Clathrin
DE   assembly protein large beta chain; (SCHPO_2.PE1384).
GN   Name=apl1; ORFNames=SPBC2G2.06c;
OS   SCHIZOSACCHAROMYCES POMBE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SCHPO_2.PE1384.
CC       Schizosaccharomyces pombe chromosome II EF1 full sequence 1..4539804
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:AP2B_SCHPO
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which
CC       link clathrin to receptors in coated vesicles. Clathrin-associated
CC       protein complexes are believed to interact with the cytoplasmic
CC       tails of membrane proteins, leading to their selection and
CC       concentration. Beta adaptin is a subunit of the plasma membrane
CC       adaptor (By similarity).
CC   -!- SUBUNIT: Assembly protein complex 2 (AP-2) is a heterotetramer
CC       composed of two large adaptins (alpha-type subunit apl3 and beta-
CC       type subunit apl1), a medium chain (mu-type subunit apm4) and a
CC       small adaptin (sigma-type subunit aps2) (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane (By similarity). Membrane,
CC       coated pit; Peripheral membrane protein; Cytoplasmic side (By
CC       similarity). Note=Component of the coat surrounding the
CC       cytoplasmic face of coated vesicles in the plasma membrane (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC   -!- GENE_FAMILY: HOG000163270 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Schizosaccharomyces_pombe;SPBC2G2.06C;SPBC2G2.06C-1;SPBC2G2.06C-1.
DR   UniProtKB/Swiss-Prot; O43005; -.
DR   EMBL; CU329671; CAA17886.1; -; Genomic_DNA.
DR   PIR; T40145; T40145.
DR   RefSeq; NP_596435.1; NM_001022354.1.
DR   ProteinModelPortal; O43005; -.
DR   STRING; O43005; -.
DR   EnsemblFungi; SPBC2G2.06c-1; SPBC2G2.06c-1; SPBC2G2.06c.
DR   GeneID; 2540375; -.
DR   GenomeReviews; CU329671_GR; apl1.
DR   KEGG; spo:SPBC2G2.06c; -.
DR   NMPDR; fig|4896.1.peg.2301; -.
DR   GeneDB_Spombe; SPBC2G2.06c; -.
DR   eggNOG; fuNOG04097; -.
DR   GeneTree; EFGT00050000000022; -.
DR   OMA; VLKWATE; -.
DR   OrthoDB; EOG476P7N; -.
DR   PhylomeDB; O43005; -.
DR   ArrayExpress; O43005; -.
DR   GO; GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_Spombe.
DR   GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB_Spombe.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IDA:GeneDB_Spombe.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR016342; AP_complex_bsu.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   Gene3D; G3DSA:1.25.10.10; ARM-like; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SUPFAM; SSF48371; ARM-type_fold; 1.
DR   HOGENOMDNA; SCHPO_2.PE1384; -.
KW   SPBC2G2.06cccc7236820036002503210000011;
KW   O43005;
KW   Cell membrane; Coated pit; Complete proteome; Membrane;
KW   Reference proteome.
SQ   SEQUENCE   677 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSSSSSHFSS TAADLLAVFS SDNKDKSANK RISALKKAIA GISYGYDMSS LFPSVISSME
     SNNLELKKLC YLYLKIYASV KPTEAKRAVK LILNDIYSSN PMIRSLALRT LTSVNIKNFW
     VAAMDPIVRL LDDTDPYVRK TAAIGIAKLY SYDKKMVESS GLIDHLKEML SDESSVVVAN
     SLAALMNIVN SSTGFKLTFS REISNKLVKS LTDCSEWLQV AILDALIFYV PQKPGEAESF
     AERISPWLQH GNAAVCMGAV KVILYLTNYM KDDNRVKEYF MKTQPPLVTL LARKSSATQY
     VILRNIQIIL EQCPEMFAND IHFFYCNFDD PIYVKLEKLD ILTKIADIHN LDQILPEFVE
     YASEIDVELV RKSVKCIGYL AIKIEERKND CIDSLIELMN TKVTYVIQEA VIVIRDILRK
     YPGSYKSLVP ILYENLDSLD EPDAKSAVIW ILGQYAEEIE DSITLLNDYL KGFFDEPLEI
     QLTLLTAVIK VFLKKPTAAA DMVTNVLQWC TDEVNDPDLR DRGIIYSRML SANPELAKKV
     ILANMPPVNV GTGMYDPDTT EQLMLNISTL SSIYHKPPNR FVKGAQVAYC EPSPVLRLRT
     RDSNPSNTDS RESNHKKYNH FHQKSQTRRV MEQYDRNSWN PSPFSDESNS NTFSGKFDSA
     DQENLGMPMT PETHLMD
//

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