(data stored in ACNUC7421 zone)

HOGENOM: SCHPO_2_PE1557

ID   SCHPO_2_PE1557                       STANDARD;      PRT;   359 AA.
AC   SCHPO_2_PE1557; O60185;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (SCHPO_2.PE1557).
GN   Name=mri1; ORFNames=SPBC23E6.10c;
OS   SCHIZOSACCHAROMYCES POMBE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SCHPO_2.PE1557.
CC       Schizosaccharomyces pombe chromosome II EF1 full sequence 1..4539804
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:MTNA_SCHPO
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Schizosaccharomyces_pombe;SPBC23E6.10C;SPBC23E6.10C-1;SPBC23E6.10C-1.
DR   UniProtKB/Swiss-Prot; O60185; -.
DR   EMBL; CU329671; CAA18878.1; -; Genomic_DNA.
DR   PIR; T39944; T39944.
DR   RefSeq; NP_596610.1; NM_001022531.1.
DR   HSSP; Q06489; 1W2W.
DR   ProteinModelPortal; O60185; -.
DR   STRING; O60185; -.
DR   EnsemblFungi; SPBC23E6.10c-1; SPBC23E6.10c-1; SPBC23E6.10c.
DR   GeneID; 2540540; -.
DR   GenomeReviews; CU329671_GR; mri1.
DR   KEGG; spo:SPBC23E6.10c; -.
DR   NMPDR; fig|4896.1.peg.2476; -.
DR   GeneDB_Spombe; SPBC23E6.10c; -.
DR   eggNOG; fuNOG06631; -.
DR   GeneTree; EFGT00050000003245; -.
DR   OMA; EDGWKVI; -.
DR   OrthoDB; EOG4S1XGM; -.
DR   PhylomeDB; O60185; -.
DR   ArrayExpress; O60185; -.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_Spombe.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB_Spombe.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; SCHPO_2.PE1557; -.
KW   SPBC23E6.10ccc7236820036002503210000011;
KW   O60185;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus; Reference proteome.
SQ   SEQUENCE   359 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLQAIIYNE DKLLVLDQLL LPYERKYISV SNVEDAFAVI KKMQVRGAPA IAIVAALSVA
     VGLKHLSEDA DAKEYVINSF EHLKQSRPTA VNLFETAKFM QGIALQEGKN CRNKIIQEAE
     RMLVKDLEDN HNIGTAGRKF LLQHYKDKDK LTVLTHCNTG SLATSGYGTA LGIIRSLHES
     GNLEHAYCTE TRPYNQGSRL TAFELVHDKI PATLVTDSTV ASIMHKIDAI VVGADRVTRN
     GDTANKIGTY NLAILAKHFG KPFIVAAPFS SIDTSLASGS QITIEQRPPI EMTTITGPII
     TDSNSRNLED PKRVRISIAA PGIDVYSPAF DVTPANLITA IATEKGFYTQ QTNNKYDFS
//

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