(data stored in ACNUC14511 zone)

HOGENOM: SCHPO_2_PE308

ID   SCHPO_2_PE308                        STANDARD;      PRT;   351 AA.
AC   SCHPO_2_PE308; O59703;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Geranylgeranyl pyrophosphate synthase; Short=GGPP synthase;
DE   Short=GGPPSase;AltName: Full=(2E,6E)-farnesyl diphosphate
DE   synthase;AltName: Full=Dimethylallyltranstransferase; EC=2.5.1.1;AltName:
DE   Full=Farnesyl diphosphate synthase;AltName:
DE   Full=Farnesyltranstransferase; EC=2.5.1.29;AltName: Full=Geranylgeranyl
DE   diphosphate synthase;AltName: Full=Geranyltranstransferase; EC=2.5.1
DE   10;AltName: Full=Sporulation-specific protein 9; (SCHPO_2.PE308).
GN   Name=spo9; ORFNames=SPBC36.06c;
OS   SCHIZOSACCHAROMYCES POMBE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SCHPO_2.PE308.
CC       Schizosaccharomyces pombe chromosome II EF1 full sequence 1..4539804
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:GGPPS_SCHPO
CC   -!- FUNCTION: Catalyzes the trans-addition of the 3 molecules of IPP
CC       onto DMAPP to form geranylgeranyl pyrophosphate. Required for the
CC       membrane attachment of ypt7 and rhb1. May be involved in vesicle
CC       trafficking and protein sorting. Required for forespore membrane
CC       formation.
CC   -!- CATALYTIC ACTIVITY: Dimethylallyl diphosphate + isopentenyl
CC       diphosphate = diphosphate + geranyl diphosphate.
CC   -!- CATALYTIC ACTIVITY: Geranyl diphosphate + isopentenyl diphosphate
CC       = diphosphate + (2E,6E)-farnesyl diphosphate.
CC   -!- CATALYTIC ACTIVITY: (2E,6E)-farnesyl diphosphate + isopentenyl
CC       diphosphate = diphosphate + geranylgeranyl diphosphate.
CC   -!- COFACTOR: Binds 3 magnesium ions per subunit (By similarity).
CC   -!- PATHWAY: Isoprenoid biosynthesis; farnesyl diphosphate
CC       biosynthesis; farnesyl diphosphate from geranyl diphosphate and
CC       isopentenyl diphosphate: step 1/1.
CC   -!- PATHWAY: Isoprenoid biosynthesis; geranyl diphosphate
CC       biosynthesis; geranyl diphosphate from dimethylallyl diphosphate
CC       and isopentenyl diphosphate: step 1/1.
CC   -!- PATHWAY: Isoprenoid biosynthesis; geranylgeranyl diphosphate
CC       biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate
CC       and isopentenyl diphosphate: step 1/1.
CC   -!- SUBUNIT: Interacts with fps1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC   -!- GENE_FAMILY: HOG000160912 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Schizosaccharomyces_pombe;SPBC36.06C;SPBC36.06C-1;SPBC36.06C-1.
DR   UniProtKB/Swiss-Prot; O59703; -.
DR   EMBL; CU329671; CAA19054.1; -; Genomic_DNA.
DR   PIR; T40301; T40301.
DR   RefSeq; NP_595334.1; NM_001021242.1.
DR   HSSP; P14324; 1ZW5.
DR   ProteinModelPortal; O59703; -.
DR   STRING; O59703; -.
DR   EnsemblFungi; SPBC36.06c-1; SPBC36.06c-1; SPBC36.06c.
DR   GeneID; 2540933; -.
DR   GenomeReviews; CU329671_GR; spo9.
DR   KEGG; spo:SPBC36.06c; -.
DR   NMPDR; fig|4896.1.peg.1200; -.
DR   GeneDB_Spombe; SPBC36.06c; -.
DR   eggNOG; fuNOG05213; -.
DR   GeneTree; EFGT00050000002300; -.
DR   OMA; MELANEN; -.
DR   OrthoDB; EOG4NPBDJ; -.
DR   PhylomeDB; O59703; -.
DR   ArrayExpress; O59703; -.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_Spombe.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB_Spombe.
DR   GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:EC.
DR   GO; GO:0004311; F:farnesyltranstransferase activity; IEA:EC.
DR   GO; GO:0004337; F:geranyltranstransferase activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:GeneDB_Spombe.
DR   GO; GO:0004660; F:protein farnesyltransferase activity; IMP:GeneDB_Spombe.
DR   GO; GO:0030437; P:ascospore formation; IMP:GeneDB_Spombe.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR008949; Terpenoid_synth.
DR   Gene3D; G3DSA:1.10.600.10; Terpenoid_synth; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SUPFAM; SSF48576; Terpenoid_synth; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
DR   HOGENOMDNA; SCHPO_2.PE308; -.
KW   SPBC36.06cc6cc7236820036002503210000011;
KW   O59703;
KW   Carotenoid biosynthesis; Complete proteome; Cytoplasm;
KW   Isoprene biosynthesis; Magnesium; Metal-binding; Nucleus;
KW   Protein transport; Reference proteome; Transferase; Transport.
SQ   SEQUENCE   351 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVNDFNEKNG IKKRLLDFFP VVLEGIREIL ESMQYFPEET EKLLYSIKRN TLGGKNNRGL
     AVLQSLTSLI NRELEEAEFR DAALLGWLIE ILQGCFLMAD DIMDQSIKRR GLDCWYLVVG
     VRRAINESQL LEACIPLLIR KYFRNMPYYV DLLDTFREVT FLTELGQQED LLSSRDGEAS
     LRSFDLMKYD FIITYKTSFY SFYLPIKCAL LLSRNSNQKA YDTTIKLSKL LGYYFQVQDD
     YLDCFGDYTV LGKVGMDIQD NKCTWLVCYA EKFASADQLN LLRAHYGKAG SENIAVIKQL
     YHELQIPELY HKFEDDMVDS ISKEIDLIDE STGLKKCIFT KFFQLIYKRS R
//

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