(data stored in ACNUC30630 zone)

HOGENOM: SCHPO_3_PE652

ID   SCHPO_3_PE652                        STANDARD;      PRT;   489 AA.
AC   SCHPO_3_PE652; O94582; P78905;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable anthranilate synthase component 1; EC=4.1.3
DE   27;AltName: Full=Anthranilate synthase component I; (SCHPO_3.PE652).
GN   Name=trp3; ORFNames=SPCC1442.09;
OS   SCHIZOSACCHAROMYCES POMBE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=4896;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SCHPO_3.PE652.
CC       Schizosaccharomyces pombe chromosome III EF1 full sequence 1..2452883
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:TRPE_SCHPO
CC   -!- CATALYTIC ACTIVITY: Chorismate + L-glutamine = anthranilate +
CC       pyruvate + L-glutamate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 1/5.
CC   -!- SUBUNIT: Tetramer of two components I and two components II (By
CC       similarity).
CC   -!- MISCELLANEOUS: Component I catalyzes the formation of anthranilate
CC       using ammonia rather than glutamine, whereas component II provides
CC       glutamine amidotransferase activity.
CC   -!- SIMILARITY: Belongs to the anthranilate synthase component I
CC       family.
CC   -!- GENE_FAMILY: HOG000025142 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Schizosaccharomyces_pombe;SPCC1442.09;SPCC1442.09-1;SPCC1442.09-1.
DR   UniProtKB/Swiss-Prot; O94582; P78905; -.
DR   EMBL; CU329672; CAA21443.1; -; Genomic_DNA.
DR   EMBL; D89256; BAA13917.1; -; mRNA.
DR   PIR; T40974; T40974.
DR   PIR; T43181; T43181.
DR   RefSeq; NP_588323.1; NM_001023314.1.
DR   ProteinModelPortal; O94582; -.
DR   STRING; O94582; -.
DR   EnsemblFungi; SPCC1442.09-1; SPCC1442.09-1; SPCC1442.09.
DR   GeneID; 2538842; -.
DR   GenomeReviews; CU329672_GR; trp3.
DR   KEGG; spo:SPCC1442.09; -.
DR   NMPDR; fig|4896.1.peg.661; -.
DR   GeneDB_Spombe; SPCC1442.09; -.
DR   eggNOG; fuNOG04537; -.
DR   GeneTree; EFGT00050000003836; -.
DR   OMA; SDEKQCA; -.
DR   OrthoDB; EOG4KH63B; -.
DR   PhylomeDB; O94582; -.
DR   BioCyc; SPOM-XXX-01:SPOM-XXX-01-000246-MON; -.
DR   ArrayExpress; O94582; -.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB_Spombe.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB_Spombe.
DR   GO; GO:0004049; F:anthranilate synthase activity; IEA:EC.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR019999; Anth_synth_I.
DR   InterPro; IPR006805; Anth_synth_I_N.
DR   InterPro; IPR005256; Anth_synth_I_PabB.
DR   InterPro; IPR015890; Chorismate-bd_C.
DR   Gene3D; G3DSA:3.60.120.10; TRPE_1_chor_bd; 1.
DR   Pfam; PF04715; Anth_synt_I_N; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   PRINTS; PR00095; ANTSNTHASEI.
DR   SUPFAM; SSF56322; TRPE_1_chor_bd; 1.
DR   TIGRFAMs; TIGR00564; TrpE_most; 1.
DR   HOGENOMDNA; SCHPO_3.PE652; -.
KW   SPCC1442.09ccc7236820036002503210000011;
KW   O94582;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Lyase; Phosphoprotein; Reference proteome;
KW   Tryptophan biosynthesis.
SQ   SEQUENCE   489 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKIYPDLKQV QELAEKHKAN KIPIYGVIPA DMLTPSVAYL KLNQGKKYSF ILESVTQGES
     VSRYSFIGSP YRILMANGKT DPLARLEREL KEVKTAPVEG LPSFSGGAVG YVSYDCIKYF
     EPTTEMPLED TLGLPEAMFF MTDDLVAFDH AYQTVKIISH VCIQQGRPIE EAYEAAVFKI
     NMLKKKLESP EIPLPEQKKV HLGYEAKSNV GEDGYKAFVS NLKEHIFNGD IFQAVPSQRI
     ARRTDLHPFN LYRHLRTVNP SPYMFYIHCD DFDIIGASPE LLVKSEHGRI INHPIAGTVP
     RGKTKEEDEA YAKDLLASVK DRAEHVMLVD LARNDVSRVC DLDTTSVDKL MTIEKFSHVQ
     HLVSQVSGVL RPDKTRFDAF RSIFPAGTVS GSPKVRAIQL VYGLEKEKRG IYAGAVGRWG
     YEDDNMDTCI AIRTMVYKDG TVYLQAGGGI VFDSDEQDEY VETLNKLRSN VTAIEETEKL
     YAEEENSSA
//

If you have problems or comments...

PBIL Back to PBIL home page