(data stored in ACNUC7421 zone)

HOGENOM: SHIF8_1_PE1008

ID   SHIF8_1_PE1008                       STANDARD;      PRT;   402 AA.
AC   SHIF8_1_PE1008; Q0T5W7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Multidrug resistance protein mdtH; (SHIF8_1.PE1008).
GN   Name=mdtH; OrderedLocusNames=SFV_1087;
OS   SHIGELLA FLEXNERI 5 STR. 8401.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SHIF8_1.PE1008.
CC       Shigella flexneri 5 str. 8401, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:MDTH_SHIF8
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. DHA1
CC       family. MdtH (TC 2.A.1.2.21) subfamily.
CC   -!- GENE_FAMILY: HOG000266157 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q0T5W7; -.
DR   EMBL; CP000266; ABF03298.1; -; Genomic_DNA.
DR   RefSeq; YP_688603.1; NC_008258.1.
DR   ProteinModelPortal; Q0T5W7; -.
DR   STRING; Q0T5W7; -.
DR   EnsemblBacteria; EBESCT00000094580; EBESCP00000090776; EBESCG00000093624.
DR   GeneID; 4209569; -.
DR   GenomeReviews; CP000266_GR; SFV_1087.
DR   KEGG; sfv:SFV_1087; -.
DR   eggNOG; COG0477; -.
DR   GeneTree; EBGT00050000008823; -.
DR   OMA; LSMIPIG; -.
DR   ProtClustDB; PRK11646; -.
DR   BioCyc; SFLE373384:SFV_1087-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   HAMAP; MF_01529; MFS_MdtH; 1; -.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   InterPro; IPR022855; Multidrug-R_MdtH.
DR   PANTHER; PTHR24003:SF97; PTHR24003:SF97; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   HOGENOMDNA; SHIF8_1.PE1008; -.
KW   multidrug resistance protein MdtH;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   402 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSRVSQARNL GKYFLLIDNM LVVLGFFVVF PLISIRFVDQ MGWAAVMVGI ALGLRQFIQQ
     GLGIFGGAIA DRFGAKPMIV TGMLMRAAGF ATMGIAHEPW LLWFSCLLSG LGGTLFDPPR
     SALVVKLIRP QQRGRFFSLL MMQDSASAVI GALLGSWLLQ YDFRLVCATG PVLFVLCAAF
     NAWLLPAWKL STVRTPVREG MTRVMRDKRF VTYVLTLAGY YMLAVQVMLM LPIMVNDVAG
     APSAVKWMYA IEACLSLTLL YPIARWSEKH FRLEHRLMAG LLIMSLSMMP VGMVSGLQQL
     FTLICLFYIG SIIAEPARET LSASLADARA RGSYMGFSRL GLAIGGAIGY IGGGWLFDLG
     KSAHQPELPW MMLGIIGIFT FLALGWQFSQ KRAARRLLER DA
//

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