(data stored in ACNUC7421 zone)

HOGENOM: SHISS_1_PE1010

ID   SHISS_1_PE1010                       STANDARD;      PRT;   402 AA.
AC   SHISS_1_PE1010; Q3Z351;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Multidrug resistance protein mdtH; (SHISS_1.PE1010).
GN   Name=mdtH; OrderedLocusNames=SSON_1085;
OS   SHIGELLA SONNEI SS046.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SHISS_1.PE1010.
CC       Shigella sonnei Ss046, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:MDTH_SHISS
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. DHA1
CC       family. MdtH (TC 2.A.1.2.21) subfamily.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAZ87811.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000266157 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q3Z351; -.
DR   EMBL; CP000038; AAZ87811.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_310046.2; NC_007384.1.
DR   ProteinModelPortal; Q3Z351; -.
DR   STRING; Q3Z351; -.
DR   EnsemblBacteria; EBESCT00000101092; EBESCP00000097121; EBESCG00000100136.
DR   GeneID; 3670113; -.
DR   GenomeReviews; CP000038_GR; SSON_1085.
DR   KEGG; ssn:SSON_1085; -.
DR   eggNOG; COG0477; -.
DR   GeneTree; EBGT00050000008823; -.
DR   PhylomeDB; Q3Z351; -.
DR   ProtClustDB; PRK11646; -.
DR   BioCyc; SSON300269:SSO_1085-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   HAMAP; MF_01529; MFS_MdtH; 1; -.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   InterPro; IPR022855; Multidrug-R_MdtH.
DR   PANTHER; PTHR24003:SF97; PTHR24003:SF97; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   HOGENOMDNA; SHISS_1.PE1010; -.
KW   multidrug resistance protein MdtH;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   402 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSRVSQARNL GKYFLLIDNM LVVLGFFVVF PLISIRFVDQ MGWAAVMVGI ALGLRQFIQQ
     GLGIFGGAIA DRFGAKPMIV TGMLMRAAGF ATMGIAHEPW LLWFSCLLSG LGGTLFDPPR
     SALVVKLIRP QQRCRFFSLL MMQDSAGAVI GALLGSWLLQ YDFRLVCATG AVLFVLCAAF
     NAWLLPAWKL STVRTPVREG MTRVMRDKRF VTYVLTLAGY YMLAVQVMLM LPIMVNDVAG
     APSAVKWMYA IEACLSLTLL YPIARWSEKH FRLEHRLMAG LLIMSLSMMP VGMVSGLQQL
     FTLICLFYIG SIIAEPARET LSALLADARA RGSYMGFSRL GLAIGGAIGY IGGGWLFDLG
     KSAHQPELPW MMLGIIGIFT FLALGWQFSQ KRATRRLLER DA
//

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