(data stored in SCRATCH9089 zone)

HOGENOM6: SIMEL1_2_PE1204

ID   SIMEL1_2_PE1204                      STANDARD;      PRT;   758 AA.
AC   SIMEL1_2_PE1204; Q59749;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (SIMEL1_2.PE1204).
GN   Name=parC; OrderedLocusNames=R01199; ORFNames=SMc01761;
OS   SINORHIZOBIUM MELILOTI 1021.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae;
OC   Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SIMEL1_2.PE1204.
CC       Sinorhizobium meliloti 1021, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:PARC_RHIME
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule
CC       (By similarity).
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q59749; -.
DR   EMBL; AL591688; CAC45778.1; -; Genomic_DNA.
DR   EMBL; X95674; CAA64977.1; -; Genomic_DNA.
DR   RefSeq; NP_385305.1; NC_003047.1.
DR   ProteinModelPortal; Q59749; -.
DR   GeneID; 1232843; -.
DR   GenomeReviews; AL591688_GR; R01199.
DR   KEGG; sme:SMc01761; -.
DR   NMPDR; fig|266834.1.peg.2493; -.
DR   OMA; HNAAELC; -.
DR   ProtClustDB; PRK05561; -.
DR   BioCyc; SMEL266834:SMC01761-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 2.
DR   Pfam; PF03989; DNA_gyraseA_C; 3.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; SIMEL1_2.PE1204; -.
DR   PRODOM; SIMEL1_2_PE1204.
DR   SWISS-2DPAGE; SIMEL1_2_PE1204.
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Topoisomerase.
SQ   SEQUENCE   758 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGQSLLPPSG GDDNIQPVDL KAALEERYLA YALSTIMHRA LPDVRDGLKP VHRRIIHAMS
     EMGLRPNSSF KKCARIVGDV IGKFHPHGDQ SVYDALVRLA QDFSQRYPVV DGQGNFGNID
     GDNAAAYRYT EAKMTEVAAL LLEGIDQDAV DFRPTYNEED QEPTVLPGAF PNLLANGASG
     IAVGMATSIP PHNAHELCDA ALHLIKHPDA TVEDLLFDPA NPQRGGIEGP DFPTGGVIVE
     SRASMAESYR TGRGGFRVRA RWAVEDLGRG GFQIVVTEIP YQVQKSRLIE KIAELLIARK
     LPLLEDIRDE SAEDVRVVLV PKSRSVDANI LMESLFKLTE LESRIPLNMN VLSMGRVPRV
     MALNEVLSEW LAHRREVLQR RSRHRLAAID RRLEILGGYL IAYLNIDEVI RIIREEDEPK
     AVMIERFGLT DVQAEAILNM RLRSLRKLEE FEIRTEFDSL SKEKAEIEAL LASGDKQWQA
     VAWEIGEVKK KFAKATELGK RRSTFSDAPD ADVEAIQQAM IEKEPITVVI SEKGWIRALK
     GHIADTSSLQ FKDGDGLKVS FPAQTTDKIL IFTTGGKAYT LGGDKLPGGR GHGEPLRIMV
     DMENDQDVLT AFVHDPARKL IVSSTAGNGF VVTESDIVAN TRKGKQVMNV TMPDEAKLVV
     PVKGDHLAVV GENRKMLVFP LVQVPEMARG KGVRLQRYKD GGVSDIRSFA IAEGLTWEDS
     AGRVFTKTRD ELIEWMGDRA GAGRVVPKGF PRSGKFSG
//

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