(data stored in SCRATCH3701 zone)

HOGENOM6: SPHTD_1_PE1716

ID   SPHTD_1_PE1716                       STANDARD;      PRT;   836 AA.
AC   SPHTD_1_PE1716; D1C4I8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (SPHTD_1.PE1716).
GN   OrderedLocusNames=Sthe_1721;
OS   SPHAEROBACTER THERMOPHILUS DSM 20745.
OC   Bacteria; Chloroflexi; Sphaerobacteridae; Sphaerobacterales;
OC   Sphaerobacterineae; Sphaerobacteraceae; Sphaerobacter.
OX   NCBI_TaxID=479434;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SPHTD_1.PE1716.
CC       Sphaerobacter thermophilus DSM 20745 chromosome 1, complete genome.
CC       sequence 1..690592 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:D1C4I8_SPHTD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D1C4I8; -.
DR   EMBL; CP001823; ACZ39155.1; -; Genomic_DNA.
DR   RefSeq; YP_003319977.1; NC_013523.1.
DR   GeneID; 8639146; -.
DR   GenomeReviews; CP001823_GR; Sthe_1721.
DR   KEGG; sti:Sthe_1721; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; SPHTD_1.PE1716; -.
DR   PRODOM; SPHTD_1_PE1716.
DR   SWISS-2DPAGE; SPHTD_1_PE1716.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   836 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDIGTVRQID IDVEMRRSYL DYAMSVIVQR ALPDVRDGLK PVQRRILYAM HEMGLRPQSR
     FRKSAGIVGE VLKLYHPHSD SAVYDALVRM VQPFSLRYPL VEGQGNFGSV DGDSAAAMRY
     TEAKLAAISE EMLQDIDKNT VDFKPNYDGE AQEPVVLPAK LPNLLVNGAA GIAVGMATNI
     PPHNLAEVCD GLIMLIDNPE ATSDDLLEVI QGPDFPTGGV ILGREGIRAA YATGKGRVVI
     RARTHIEEMP RGNRYQIIVT ELPYQVNKAA LLEKIAELVK AGRIEGIHDL RDESDRTGMR
     MVIELKRDAQ PQRVLNALFK HTQLQQTFGV NMLALVDGTQ PRVLTLRRLL QLYLDHRQEV
     VRRRTEHELG RARRRAHILE GLKIALDHLD EVIQTIRQSQ TIESARTNLI NRFGFTEVQA
     NAILDMQLRR LAALERHKIE NEYRDLLKEI AGLEELLADP AKILAVIREE LVQLRDKFGD
     ERRTLIQDVS GEITDEDLIP DVSVLVMITN RGYVKRIADG TYRQQHRGGR GVTGMTLREE
     DGVHRIVAAR THDSLLFFTD RGRVFQLKVW ELPDSGRTAR GIPVINLIGI EPGETITALL
     PVRDFASARY LFMCTRNGRV KRTRLDQFAS VRSSGLIAIG LEEGDELAWV RLTSGNDELI
     LVTEQGQAIR FKETDVRPMG RPAAGVIGIR MEPGDRVIAA EVVQPDQDLL VVSANGYGKR
     TALSEFRVQG RGGQGVTAMK ITERNGPVAA ARVVTDTDSI MLVSLRGMVI RVPAEQISRI
     GRMTQGVSIM RLQEQDQVAS VTVIRTPEDA EMADLEEASA DTSETAGAAR DEAAGE
//

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