(data stored in SCRATCH3701 zone)

HOGENOM6: SPHWW_3_PE4528

ID   SPHWW_3_PE4528                       STANDARD;      PRT;   936 AA.
AC   SPHWW_3_PE4528; A5VF35;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (SPHWW_3.PE4528).
GN   OrderedLocusNames=Swit_4563;
OS   SPHINGOMONAS WITTICHII RW1.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=392499;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SPHWW_3.PE4528.
CC       Sphingomonas wittichii RW1, complete genome.
CC       sequence 1..690592 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:A5VF35_SPHWW
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A5VF35; -.
DR   EMBL; CP000699; ABQ70901.1; -; Genomic_DNA.
DR   RefSeq; YP_001265039.1; NC_009511.1.
DR   ProteinModelPortal; A5VF35; -.
DR   SMR; A5VF35; 54-536.
DR   STRING; A5VF35; -.
DR   GeneID; 5196588; -.
DR   GenomeReviews; CP000699_GR; Swit_4563.
DR   KEGG; swi:Swit_4563; -.
DR   NMPDR; fig|392499.4.peg.4583; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; SPHWW_3.PE4528; -.
DR   PRODOM; SPHWW_3_PE4528.
DR   SWISS-2DPAGE; SPHWW_3_PE4528.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   936 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTAPFRGQNT ASTNTDPKTL ASVPPPIENS DISPISIIDE MKSSYLDYAM SVIVSRALPD
     VRDGLKPVHR RILYACQEGG FVPGRPYRKS AKIVGDVMGN YHPHGDSSIY DALARLAQDW
     AMRVPLIDGQ GNFGSMDPDP PASMRYTEAR LAKVAMTLLD DLDKDTVNFT PNYDGSRDEP
     QVLPARFPNI LVNGAGGIAV GMATNIPPHN LGEVIAACKA YVDNPAISID ELMAIVPGPD
     FPTGALILGQ SGARQAYHTG RGSIIMRSRH EVEESRGDRR SIVLTEIPYQ VGKSGLVEKI
     AEAAKDKRIE GISDIRDESN RQGVRIVMDL KRDATPDVVL NQLWRHTPAQ TSFPANMLAI
     RGGRPETLNL RDIVESFVKF REEVITRRSK FELNKARERA HILLGLVIAV TNLDEVVRII
     RRSASPAEAR AALISREWPR GEIESYIKLV EAVDTIGDAP TYQLSEVQVR AILDLRLHRL
     TALGRDEIGD ELAKLAESIA ELLEILGNRV RLYQVMVEEF DAILVEFATP RRTEIAPAGD
     DIDDEDLIER EDMVVTVTHG GYIKRTPLEA FRAQRRGGKG RSGMATKDED AVTELFVTST
     HTPVLFFSNH GKVYRKKVWR LPEGAPQARG RPMINLLPLA DGEKITTVLP LPEDEESWST
     LHVVFATAHG NVRRNSMDAF ANVPTNGKFA MRFDEDATDR LIGVALLTEQ DDVLLATRGG
     KAIRFASTDV REFQSRTSTG VRGILLKGDD EVISLSILKG FDASTDERDA YLRAAPWKDN
     EADPTLSAER MAEFEAAEEF ILTVCANGYG KRSSAYEYRR TGRGGQGIGN IDNLERNGPV
     VASFPAHNGE QLMLVTDQAK LIRLSVGDTR VIGRNSAGVR LFNVSDNEHV VGAARIEESD
     DEAEADLGDG TGEIAPADDA VVGEDLADGG EASGDE
//

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