(data stored in ACNUC7421 zone)

HOGENOM: SPISS_1_PE1

ID   SPISS_1_PE1                          STANDARD;      PRT;   471 AA.
AC   SPISS_1_PE1; E1R6M9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (SPISS_1.PE1).
GN   Name=dnaA; OrderedLocusNames=Spirs_0001;
OS   SPIROCHAETA SMARAGDINAE DSM 11293.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Spirochaeta.
OX   NCBI_TaxID=573413;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SPISS_1.PE1.
CC       Spirochaeta smaragdinae DSM 11293 chromosome, complete genome.
CC       nt) ;
CC   -!- ANNOTATIONS ORIGIN:E1R6M9_SPISS
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E1R6M9; -.
DR   EMBL; CP002116; ADK79161.1; -; Genomic_DNA.
DR   RefSeq; YP_003801755.1; NC_014364.1.
DR   GeneID; 9492211; -.
DR   GenomeReviews; CP002116_GR; Spirs_0001.
DR   KEGG; ssm:Spirs_0001; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   HOGENOMDNA; SPISS_1.PE1; -.
KW   chromosomal replication initiator protein DnaA;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   471 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNTQSRWDFS IFWQEALNQL KNELSDQEFV MWFSNISYHS SEEGKLILSV PSAFYRDQVK
     QRYTGIIKEK LYELSGFQLD VDFIVTKRAT SESPKEKNEV SDTPQPPMAV KPVPVSVSPA
     KNDPPKKHPD LRPDYTFENF VIGENNTLAA NACMAISKNP GTAYNPCLIY GGVGLGKTHL
     IQSIGNYAWA HNPDIKIAYV TAETFTNEFI EAIHHNKNHQ FKNKYRKVDI LLIDDIHFLQ
     EKTGTQEELF HTFNALYETN KQLVFTCDRP VSELKQLTDR LRSRFERGLN VDLQAPAFET
     RFAILKQKVE EKKVPIDDEV IELICRNVTT NVRDLEAALT RLIAYADLLH KKVTLDIARQ
     QLKDVFSNPK MSNITVEMIQ RVTAEYFNLS PNDLRGKKRT KAIAFPRQIA MYITREITEF
     STTEVGLEFG GRDHTTVMHA CQRVESRMQT DPSLEPIIQR IVRQIKEYGT K
//

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