(data stored in ACNUC7421 zone)

HOGENOM: SPITD_1_PE1

ID   SPITD_1_PE1                          STANDARD;      PRT;   452 AA.
AC   SPITD_1_PE1; E0RTB1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (SPITD_1.PE1).
GN   Name=dnaA; OrderedLocusNames=STHERM_c00010;
OS   SPIROCHAETA THERMOPHILA DSM 6192.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Spirochaeta.
OX   NCBI_TaxID=665571;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SPITD_1.PE1.
CC       Spirochaeta thermophila DSM 6192 chromosome, complete genome.
CC       nt) ;
CC   -!- ANNOTATIONS ORIGIN:E0RTB1_SPITD
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E0RTB1; -.
DR   EMBL; CP001698; ADN00977.1; -; Genomic_DNA.
DR   RefSeq; YP_003873250.1; NC_014484.1.
DR   GeneID; 9757510; -.
DR   GenomeReviews; CP001698_GR; STHERM_c00010.
DR   KEGG; sta:STHERM_c00010; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; SPITD_1.PE1; -.
KW   chromosomal replication initiator protein DnaA;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   452 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEHAWDYSIV WKETLNLLRG VLTEQEFRLW FFEVDYYDGS EETLRIRVPS SFVRDQIKQR
     YQRLIEDKFY ELLGRKLLLD FVVEKRSLAQ ERPVSSSSPQ REIPKERPPH PQLRRDYTFE
     NFVIGENNAF AANAALAIAK NPGTAYNPCL IYGGVGLGKT HLLQSIGNSV YGEFHNLKVV
     YVTAEEFTNE FIASIQNKET HKFKTKYRNV DVLLIDDIHF FMNKTETQEE LFHTFNALYD
     ANKQMVFTCD RPVSELKNIS HRLRSRFERG LNVDLQPPSF ETRYAILKKK IEQKTVHIPD
     EVITFIAEHV TTNVRDLEAA LTKLIAYAEL VHRDITIDIA KSQLKDMFTT TKQTNITIDL
     IQKVVADYFG ITQSDLRNKK RTRTVVFPRQ IAMYIARELT EYSTTEIGEY FGGRDHTTVM
     YAIQKIESKM RTDPTLDTII AQLIREVQEG TK
//

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