(data stored in ACNUC7421 zone)

HOGENOM: SPITD_1_PE1000

ID   SPITD_1_PE1000                       STANDARD;      PRT;   190 AA.
AC   SPITD_1_PE1000; E0RSI9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable nicotinate-nucleotide adenylyltransferase;
DE   EC=2.7.7 18;AltName: Full=Deamido-NAD(+) diphosphorylase;AltName:
DE   Full=Deamido-NAD(+) pyrophosphorylase;AltName: Full=Nicotinate
DE   mononucleotide adenylyltransferase; (SPITD_1.PE1000).
GN   Name=nadD; OrderedLocusNames=STHERM_c10300;
OS   SPIROCHAETA THERMOPHILA DSM 6192.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Spirochaeta.
OX   NCBI_TaxID=665571;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SPITD_1.PE1000.
CC       Spirochaeta thermophila DSM 6192 chromosome, complete genome.
CC       nt) ;
CC   -!- ANNOTATIONS ORIGIN:E0RSI9_SPITD
CC   -!- FUNCTION: Catalyzes the reversible adenylation of nicotinate
CC       mononucleotide (NaMN) to nicotinic acid adenine dinucleotide
CC       (NaAD) (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + nicotinate ribonucleotide = diphosphate
CC       + deamido-NAD(+).
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; deamido-
CC       NAD(+) from nicotinate D-ribonucleotide: step 1/1.
CC   -!- SIMILARITY: Belongs to the nadD family.
CC   -!- GENE_FAMILY: HOG000262780 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E0RSI9; -.
DR   EMBL; CP001698; ADN01976.1; -; Genomic_DNA.
DR   RefSeq; YP_003874249.1; NC_014484.1.
DR   GeneID; 9756284; -.
DR   GenomeReviews; CP001698_GR; STHERM_c10300.
DR   KEGG; sta:STHERM_c10300; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IEA:HAMAP.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00244; NaMN_adenylyltr; 1; -.
DR   InterPro; IPR004821; Cyt_trans-rel.
DR   InterPro; IPR004820; Cytidylyltransf.
DR   InterPro; IPR005248; NAMN_adtrnsfrase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Gene3D; G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
DR   PANTHER; PTHR12039; NAMN_adtrnsfrase; 1.
DR   Pfam; PF01467; CTP_transf_2; 1.
DR   TIGRFAMs; TIGR00125; Cyt_tran_rel; 1.
DR   TIGRFAMs; TIGR00482; TIGR00482; 1.
DR   HOGENOMDNA; SPITD_1.PE1000; -.
KW   nicotinate-nucleotide adenylyltransferase;
KW   ATP-binding; Complete proteome; NAD; Nucleotide-binding;
KW   Nucleotidyltransferase; Pyridine nucleotide biosynthesis; Transferase.
SQ   SEQUENCE   190 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRVLLFGGTF NPIHVGHLFV AEEACVELGY EKVIFVPAYR PAHKVLADHD DPMHRYKMVE
     RATAGNPRFT VDDCEIRRQG TSYTLDTITY LMETLPLTGK LGLLIGDDLV PGFSSWKHAD
     ILPELVDIVI ARRTSSSPYE VPWRHTYITN TIIHISSSEI RERVAQGKAF RYLVPEPVYE
     YIVEHGLYRS
//

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