(data stored in SCRATCH3701 zone)

HOGENOM6: SPITD_1_PE2201

ID   SPITD_1_PE2201                       STANDARD;      PRT;   809 AA.
AC   SPITD_1_PE2201; E0RRS3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (SPITD_1.PE2201).
GN   OrderedLocusNames=STHERM_c22550;
OS   SPIROCHAETA THERMOPHILA DSM 6192.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Spirochaeta.
OX   NCBI_TaxID=665571;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SPITD_1.PE2201.
CC       Spirochaeta thermophila DSM 6192 chromosome, complete genome.
CC       nt) ;
CC   -!- ANNOTATIONS ORIGIN:E0RRS3_SPITD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E0RRS3; -.
DR   EMBL; CP001698; ADN03177.1; -; Genomic_DNA.
DR   RefSeq; YP_003875450.1; NC_014484.1.
DR   GeneID; 9757507; -.
DR   GenomeReviews; CP001698_GR; STHERM_c22550.
DR   KEGG; sta:STHERM_c22550; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; SPITD_1.PE2201; -.
DR   PRODOM; SPITD_1_PE2201.
DR   SWISS-2DPAGE; SPITD_1_PE2201.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   809 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADLKGKVVP VPIEEEIKES YLNYAMSVIV SRALPDVRDG LKPVQRRILY AMYEMGLRHD
     RPFKKSGRIV GDVLGKYHPH GDQSIYDALV RLAQEFSMRY PMVIGQGNFG SIDGDPPAAM
     RYTEAKLHKI AEEMLRDINK ETVDFVPNYD ESLKEPAVLP AAVPYLLING ASGIAVGMAT
     NIPPHNLGEV SRAIAAVIDN PEIPPKDLLR YVKGPDFPTG GIIFGKKGIR SAYLTGKGGV
     VVRARLSLET LRSGREAIVV TEIPYAVNKS SLLERVASLV RDKKIEGISE IRDESDRNGL
     RIVFELKRGV IPKVVINRLF SMTPLQTTFH VNALALVGGK PQTLTLKEII QHFISHRKEV
     VTRRAQYDLR KAEERAHILE GLKIALDNID EVIAIIKKSR TVDSARNNLM RRFGLSERQA
     QAILDMRLQK LTSLETRKII EELEATLKLI EELKELLGSE RKILEVVKNE TLELAKEYGD
     ERRTEIVAEE AEDLDIEDLI QKEDMVVLVS RDGLIKRMPV SAYRRQGRGG KGLMGGKLSG
     DDVVSHLFVA STHDYILFLS NEGKAYYLKV HEIPEGSRVS QGKSIRSLVQ LSPDEQVSAV
     VSVETFEEER EVFMITAKGL AKRLPVPALS NARTRGVIAI GLEKGDYLVD AFLTEGKGEV
     MIVTRRGHGL RCKEEEFRSM GRAARGVTAV KLEPGDEVCG AVPVEEGKDL LLVTSGGYGK
     RVEFSQFTAH GRGTKGQIAY KVSARTGELA AVLSVEAKDD VMIVTAQGNI IKLAVKDISV
     LGRQAAGVKV VNLEKPDYVV SVDRVAREK
//

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