(data stored in ACNUC7421 zone)

HOGENOM: STAAB_1_PE1009

ID   STAAB_1_PE1009                       STANDARD;      PRT;   321 AA.
AC   STAAB_1_PE1009; Q2YXE0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Phospho-N-acetylmuramoyl-pentapeptide-transferase; EC=2.7.8
DE   13;AltName: Full=UDP-MurNAc-pentapeptide phosphotransferase;
DE   (STAAB_1.PE1009).
GN   Name=mraY; OrderedLocusNames=SAB1046;
OS   STAPHYLOCOCCUS AUREUS RF122.
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STAAB_1.PE1009.
CC       Staphylococcus aureus RF122, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:MRAY_STAAB
CC   -!- FUNCTION: First step of the lipid cycle reactions in the
CC       biosynthesis of the cell wall peptidoglycan (By similarity).
CC   -!- CATALYTIC ACTIVITY: UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-
CC       D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-
CC       Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 4 family. MraY
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000275124 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2YXE0; -.
DR   EMBL; AJ938182; CAI80734.1; -; Genomic_DNA.
DR   RefSeq; YP_416530.1; NC_007622.1.
DR   STRING; Q2YXE0; -.
DR   EnsemblBacteria; EBSTAT00000013309; EBSTAP00000012966; EBSTAG00000013308.
DR   GeneID; 3793457; -.
DR   GenomeReviews; AJ938182_GR; SAB1046.
DR   KEGG; sab:SAB1046; -.
DR   NMPDR; fig|273036.3.peg.1281; -.
DR   eggNOG; COG0472; -.
DR   GeneTree; EBGT00050000024846; -.
DR   OMA; RFWIISM; -.
DR   PhylomeDB; Q2YXE0; -.
DR   ProtClustDB; PRK00108; -.
DR   BioCyc; SAUR273036:SAB1046-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008963; F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity; IEA:EC.
DR   GO; GO:0051992; F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   HAMAP; MF_00038; MraY; 1; -.
DR   InterPro; IPR000715; Glycosyl_transferase_4.
DR   InterPro; IPR003524; PNAcMuramoyl-5peptid_Trfase.
DR   InterPro; IPR018480; PNAcMuramoyl-5peptid_Trfase_CS.
DR   PANTHER; PTHR22926; Glyco_trans_4; 1.
DR   PANTHER; PTHR22926:SF3; PNAcPpept_trans; 1.
DR   Pfam; PF00953; Glycos_transf_4; 1.
DR   TIGRFAMs; TIGR00445; MraY; 1.
DR   PROSITE; PS01347; MRAY_1; 1.
DR   PROSITE; PS01348; MRAY_2; 1.
DR   HOGENOMDNA; STAAB_1.PE1009; -.
KW   Cell cycle; Cell division; Cell membrane; Cell shape;
KW   Cell wall biogenesis/degradation; Complete proteome; Membrane;
KW   Peptidoglycan synthesis; Transferase; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   321 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MIFVYALLAL VITFVLVPVL IPTLKRMKFG QSIREEGPQS HMKKTGTPTM GGLTFLLSIV
     ITSLVAIIFV EQANPIILLL FVTIGFGLIG FIDDYIIVVK KNNQGLTSKQ KFLAQIGIAI
     IFFVLSNVFH LVNFSTSIHI PFTNVAIPLS FAYVIFIVFL QVGFSNAVNL TDGLDGLATG
     LSIIGFTMYA IMSFVLGETA IGIFCIIMLF ALLGFLPYNI NPAKVFMGDT GSLALGGIFA
     TISIMLNQEL SLIFIGLVFV IETLSVMLQV ASFKLTGKRI FKMSPIHHHF ELIGWSEWKV
     VTVFWAVGLI SGLIGLWIGV H
//

If you have problems or comments...

PBIL Back to PBIL home page