(data stored in SCRATCH3701 zone)

HOGENOM6: STAAE_1_PE5

ID   STAAE_1_PE5                          STANDARD;      PRT;   893 AA.
AC   STAAE_1_PE5; A6QD45;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase A subunit; (STAAE_1.PE5).
GN   Name=gyrA; OrderedLocusNames=NWMN_0005;
OS   STAPHYLOCOCCUS AUREUS SUBSP. AUREUS STR. NEWMAN.
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=426430;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STAAE_1.PE5.
CC       Staphylococcus aureus subsp. aureus str. Newman, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A6QD45_STAAE
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A6QD45; -.
DR   EMBL; AP009351; BAF66277.1; -; Genomic_DNA.
DR   RefSeq; YP_001331040.1; NC_009641.1.
DR   ProteinModelPortal; A6QD45; -.
DR   SMR; A6QD45; 37-495.
DR   STRING; A6QD45; -.
DR   EnsemblBacteria; EBSTAT00000032138; EBSTAP00000031008; EBSTAG00000032136.
DR   GeneID; 5331984; -.
DR   GenomeReviews; AP009351_GR; NWMN_0005.
DR   KEGG; sae:NWMN_0005; -.
DR   eggNOG; COG0188; -.
DR   GeneTree; EBGT00050000024676; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; SAUR426430:NWMN_0005-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; STAAE_1.PE5; -.
DR   PRODOM; STAAE_1_PE5.
DR   SWISS-2DPAGE; STAAE_1_PE5.
KW   DNA gyrase A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   893 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKEELLMAEL PQSRINERNI TSEMRESFLD YAMSVIVARA LPDVRDGLKP VHRRILYGLN
     EQGMTPDKSY KKSARIVGDV MGKYHPHGDS SIYEAMVRMA QDFSYRYPLV DGQGNFGSMD
     GDGAAAMRYT EARMTKITLE LLRDINKDTI DFIDNYDGNE REPSVLPARF PNLLANGASG
     IAVGMATNIP PHNLTELING VLSLSKNPDI SIAELMEDIE GPDFPTAGLI LGKSGIRRAY
     ETGRGSIQMR SRAVIEERGG GRQRIVVTEI PFQVNKARMI EKIAELVRDK KIDGITDLRD
     ETSLRTGVRV VIDVRKDANA SVILNNLYKQ TPLQTSFGVN MIALVNGRPK LINLKEALVH
     YLEHQKTVVR RRTQYNLRKA KDRAHILEGL RIALDHIDEI ISTIRESDTD KVAMESLQQR
     FKLSEKQAQA ILDMRLRRLT GLERDKIEAE YNELLNYISE LEAILADEEV LLQLVRDELT
     EIRDRFGDDR RTEIQLGGFE NLEDEDLIPE EQIVITLSHN NYIKRLPVST YRAQNRGGRG
     VQGMNTLEED FVSQLVTLST HDHVLFFTNK GRVYKLKGYE VPELSRQSKG IPVVNAIELE
     NDEVISTMIA VKDLESEDNF LVFATKRGVV KRSALSNFSR INRNGKIAIS FREDDELIAV
     RLTSGQEDIL IGTSHASLIR FPESTLRPLG RTATGVKGIT LREGDEVVGL DVAHANSVDE
     VLVVTENGYG KRTPVNDYRL SNRGGKGIKT ATITERNGNV VCITTVTGEE DLMIVTNAGV
     IIRLDVADIS QNGRAAQGVR LIRLGDDQFV STVAKVKEDA EDETNEDEQS TSTVSEDGTE
     QQREAVVNDE TPGNAIHTEV IDSEENDEDG RIEVRQDFMD RVEEDIQQSS DEE
//

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