(data stored in ACNUC7421 zone)

HOGENOM: STAAJ_1_PE1012

ID   STAAJ_1_PE1012                       STANDARD;      PRT;   311 AA.
AC   STAAJ_1_PE1012; D9RGA5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase H; EC=2.1.1
DE   199;AltName: Full=16S rRNA m(4)C1402 methyltransferase;AltName: Full=rRNA
DE   (STAAJ_1.PE1012) (cytosine-N(4)-)-methyltransferase RsmH; .
GN   Name=mraW; Synonyms=rsmH; OrderedLocusNames=SAA6159_01030;
OS   STAPHYLOCOCCUS AUREUS SUBSP. AUREUS JKD6159.
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=869816;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STAAJ_1.PE1012.
CC       Staphylococcus aureus (strain JKD6159) chromosome, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D9RGA5_STAAJ
CC   -!- FUNCTION: Specifically methylates the N4 position of cytidine in
CC       position 1402 (C1402) of 16S rRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + cytosine(1402) in
CC       16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402)
CC       in 16S rRNA.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmH
CC       family.
CC   -!- GENE_FAMILY: HOG000049777 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D9RGA5; -.
DR   EMBL; CP002114; ADL22977.1; -; Genomic_DNA.
DR   EnsemblBacteria; EBSTAT00000063073; EBSTAP00000058515; EBSTAG00000061479.
DR   GenomeReviews; CP002114_GR; SAA6159_01030.
DR   GeneTree; EBGT00050000024888; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0071424; F:rRNA (cytosine-N4-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0070475; P:rRNA base methylation; IEA:HAMAP.
DR   HAMAP; MF_01007; 16SrRNA_methyltr_H; 1; -.
DR   InterPro; IPR002903; SAM-dep_MeTrfase_MraW.
DR   InterPro; IPR023397; SAM-dep_MeTrfase_MraW_recog.
DR   PANTHER; PTHR11265; Bact_methyltrans; 1.
DR   Pfam; PF01795; Methyltransf_5; 1.
DR   PIRSF; PIRSF004486; MraW; 1.
DR   SUPFAM; SSF81799; SSF81799; 1.
DR   TIGRFAMs; TIGR00006; TIGR00006; 1.
DR   HOGENOMDNA; STAAJ_1.PE1012; -.
KW   ADL22977.100003840820036002503210000011;
KW   Ribosomal RNA small subunit methyltransferase H ;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
SQ   SEQUENCE   311 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFHHISVMLN ETIDYLNVKE NGVYIDCTLG GAGHALYLLN QLNDDGRLIA IDQDQAAIDN
     AKEVLKDHLH KVTFVHSNFR ELTQILKDLN IEKVDGIYYD LGVSSPQLDI PERGFSYHHD
     ATLDMRMDQT QELTAYEIVN NWSYEALVKI FYRYGEEKFS KQIARRIEAH REQQPITTTL
     ELVDIIKEGI PAKARRKGGH PAKRVFQALR IAVNDELSAF EDSIEQAIEL VKVDGRISVI
     TFHSLEDRLC KQVFQEYEKG PEVPRGLPVV PEAYTPKLKR VNRKPITATE EDLDDNNRAR
     SAKLRVAEIL K
//

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