(data stored in ACNUC7421 zone)

HOGENOM: STAAM_1_PE1009

ID   STAAM_1_PE1009                       STANDARD;      PRT;   396 AA.
AC   STAAM_1_PE1009; Q99V76;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable glycolipid permease ltaA;AltName:
DE   Full=Lipoteichoic acid protein A; (STAAM_1.PE1009).
GN   Name=ltaA; OrderedLocusNames=SAV1016;
OS   STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50.
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STAAM_1.PE1009.
CC       Staphylococcus aureus subsp. aureus Mu50, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:LTAA_STAAM
CC   -!- FUNCTION: Probable permease that is required for glycolipid
CC       anchoring of LTA. May facilitate the transport of diglucosyl-
CC       diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of
CC       the cytoplasmic membrane, delivering Glc2-DAG as a substrate for
CC       LTA synthesis, thereby generating glycolipid-anchored LTA. Appears
CC       to play an important role in virulence (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. LtaA
CC       family.
CC   -!- GENE_FAMILY: HOG000279926 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q99V76; -.
DR   EMBL; BA000017; BAB57178.1; -; Genomic_DNA.
DR   RefSeq; NP_371540.1; NC_002758.2.
DR   ProteinModelPortal; Q99V76; -.
DR   STRING; Q99V76; -.
DR   EnsemblBacteria; EBSTAT00000005566; EBSTAP00000005384; EBSTAG00000005565.
DR   GeneID; 1120991; -.
DR   GenomeReviews; BA000017_GR; SAV1016.
DR   KEGG; sav:SAV1016; -.
DR   eggNOG; COG0477; -.
DR   GeneTree; EBGT00050000023933; -.
DR   OMA; ENRAAIW; -.
DR   ProtClustDB; CLSK885072; -.
DR   BioCyc; SAUR158878:SAV1016-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   HOGENOMDNA; STAAM_1.PE1009; -.
KW   hypothetical protein;
KW   Cell membrane; Complete proteome; Membrane; Transmembrane;
KW   Transmembrane helix; Transport; Virulence.
SQ   SEQUENCE   396 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDSSLNNYA NHKNFILMLI ILFLMEFARG MYILSYINFL PTVTSIAVAI TSLAFSIHFI
     ADASTNFVIG FLLKKFGTKI VLTTGFILAF TSLFLVIWFP ASPFVIIFSA MMLGIAVSPI
     WVIMLSSVEE DKRGKQMGYV YFSWLLGLLV GMVFMNLLIK VHPTRFAFMM SLVVLIAWIL
     YYFVDVKLTN YNTRPVKAQL RQIVDVTKRH LLLFPGILLQ GAAIAALVPI LPTYATKVIN
     VSTIEYTVAI IIGGIGCAVS MLFLSKLIDN RSRNFMYGVI LSGFILYMIL IFTLSMIVNI
     HIVWIIALAI GLMYGILLPA WNTFMARFIK SDEQEETWGV FNSIQGFGSM IGPLFGGLIT
     QFTNDLNNTF YFSALIFLVL AVFYGSYFIA NREKAK
//

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