(data stored in ACNUC1104 zone)

HOGENOM: STAAM_2_PE32

ID   STAAM_2_PE32                         STANDARD;      PRT;   514 AA.
AC   STAAM_2_PE32; P0A0J8; P23215;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Antiseptic resistance protein; (STAAM_2.PE32).
GN   Name=qacA; OrderedLocusNames=SAVP032;
OS   STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50.
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STAAM_2.PE32.
CC       Staphylococcus aureus subsp. aureus Mu50 plasmid VRSAp, complete sequen
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:QACA_STAAM
CC   -!- FUNCTION: Confers export-mediated resistance against antiseptic
CC       and disinfectant compounds such as intercalating dyes, quaternary
CC       ammonium salts and diamidines (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC   -!- GENE_FAMILY: HOG000239124 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P0A0J8; P23215; -.
DR   EMBL; AP003367; BAB47540.1; -; Genomic_DNA.
DR   RefSeq; NP_115321.1; NC_002774.1.
DR   ProteinModelPortal; P0A0J8; -.
DR   STRING; P0A0J8; -.
DR   EnsemblBacteria; EBSTAT00000008294; EBSTAP00000008029; EBSTAG00000008293.
DR   GeneID; 1119948; -.
DR   GenomeReviews; AP003367_GR; SAVP032.
DR   KEGG; sav:SAVP032; -.
DR   eggNOG; COG0477; -.
DR   GeneTree; EBGT00050000023931; -.
DR   OMA; MTILIMA; -.
DR   ProtClustDB; CLSK507148; -.
DR   BioCyc; SAUR158878:SAVP032-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; UNKNOWN_1.
DR   HOGENOMDNA; STAAM_2.PE32; -.
KW   QacA protein;
KW   Antibiotic resistance; Cell membrane; Complete proteome; Membrane;
KW   Plasmid; Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   514 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISFFTKTTD MMTSKKRWTA LVVLAVSLFV VTMDMTILIM ALPELVRELE PSGTQQLWIV
     DIYSLVLAGF IIPLSAFADK WGRKKALLTG FALFGLVSLA IFFAESAEFV IAIRFLLGIA
     GALIMPTTLS MIRVIFENPK ERATALAVWS IASSIGAVFG PIIGGALLEQ FSWHSAFLIN
     VPFAIIAVVA GLFLLPESKL SKEKSHSWDI PSTILSIAGM IGLVWSIKEF SKEGLADIIP
     WVVIVLAITM IVIFVKRNLS SSDPMLDVRL FKKRSFSAGT IAAFMTMFAM ASVLLLASQW
     LQVVEELSPF KAGLYLLPMA IGDMVFAPIA PGLAARFGPK IVLPSGIGIA AIGMFIMYFF
     GHPLSYSTMA LALILVGAGM ASLAVASALI MLETPTSKAG NAAAVEESMY DLGNVFGVAV
     LGSLSSMLYR VFLDISSFSS KGIVGDLAHV AEESVVGAVE VAKATGIKQL ANEAVTSFND
     AFVATALVGG IIMIIISIVV YLLIPKSLDI TKQK
//

If you have problems or comments...

PBIL Back to PBIL home page