(data stored in ACNUC1104 zone)

HOGENOM: STCOE1_1_PE5037

ID   STCOE1_1_PE5037                      STANDARD;      PRT;   578 AA.
AC   STCOE1_1_PE5037; P46105;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable actinorhodin transporter; (STCOE1_1.PE5037).
GN   Name=actII-2; OrderedLocusNames=SCO5083; ORFNames=SCBAC28G1.09;
OS   STREPTOMYCES COELICOLOR A3(2).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=100226;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STCOE1_1.PE5037.
CC       Streptomyces coelicolor A3(2) chromosome, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:ACT22_STRCO
CC   -!- FUNCTION: Promotes the efflux of actinorhodin.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. EmrB
CC       family.
CC   -!- GENE_FAMILY: HOG000239124 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P46105; -.
DR   EMBL; M64683; AAA26690.1; -; Genomic_DNA.
DR   EMBL; AL939122; CAC44196.1; -; Genomic_DNA.
DR   PIR; B40046; B40046.
DR   RefSeq; NP_629233.1; NC_003888.3.
DR   ProteinModelPortal; P46105; -.
DR   GeneID; 1100524; -.
DR   GenomeReviews; AL645882_GR; SCO5083.
DR   KEGG; sco:SCO5083; -.
DR   NMPDR; fig|100226.1.peg.5038; -.
DR   OMA; ETIIAAR; -.
DR   ProtClustDB; CLSK636081; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   HOGENOMDNA; STCOE1_1.PE5037; -.
KW   actinorhodin transporter;
KW   Antibiotic resistance; Cell membrane; Complete proteome; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   578 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSSVEADEPD RATAPPSALL PEDGPGPDGT AAGPPPYARR WAALGVILGA EIMDLLDGTV
     MNVAAPAVRA DLGGSLSVIQ WITVGYTLAF AVLLVVGGRL GDIYGRKRMF VVGAVGFTAA
     SVLCSVAAGP EMLTAARFLQ GGLGALMIPQ GLGLIKQMFP PKETAAAFGA FGPAIGLGAV
     LGPIVAGFLV DADLFGTGWR SVFLINLPIG VAVIVGAVLL LPEGKAPVRP KFDVVGMALV
     TSGLTLLIFP LVQGRERGWP AWAFVLMLAG AAVLVGFVAH ELRQERRGGA TLIELSLLRR
     SRYAAGLAVA LVFFTGVSGM SLLLALHLQI GLGFSPTRAA LTMTPWSVFL VVGAILTGAV
     LGSKFGRKAL HGGLVVLALG VLIMLLTIGD QAGGLTSWEL VPGIAVAGLG MGIMIGLLFD
     IALADVDKQE AGTASGVLTA VQQLGFTVGV AVLGTLFFGL LGSQATASVD DGASRARTEL
     AAAGASTTEQ DRLLADLRVC LRESASQQDS ERTPDSCRNL QQARPAVAEA TARAWRTAHT
     ENFSTAMVRT LWVVIALLAV SFALAFRLPP KPREEEGF
//

If you have problems or comments...

PBIL Back to PBIL home page